The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs

The specification of the hepatic identity during human liver development is strictly controlled by extrinsic signals, yet it is still not clear how cells respond to these exogenous signals by activating secretory cascades, which are extremely relevant, especially in 3D self-organizing systems. Here,...

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Detalles Bibliográficos
Autores principales: Michielin, Federica, Giobbe, Giovanni G., Luni, Camilla, Hu, Qianjiang, Maroni, Ida, Orford, Michael R., Manfredi, Anna, Di Filippo, Lucio, David, Anna L., Cacchiarelli, Davide, De Coppi, Paolo, Eaton, Simon, Elvassore, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237389/
https://www.ncbi.nlm.nih.gov/pubmed/33264615
http://dx.doi.org/10.1016/j.celrep.2020.108453

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