PET NEMA IQ Phantom dataset: image reconstruction settings for quantitative PET imaging

The data presented here provide information about the role of reconstruction parameters on Positron Emission Tomography (PET) image quantification. Multiple phantom measurements in four different Spheres to Background Ratio (SBR) were performed on Biograph 6 TruePoint TrueV PET/CT scanner. PET raw data were reconstructed with/without resolution recovery algorithm using six various iteration x subsets with five different Full-Width Half-Maximum (FWHM) values of Gaussian post-smoothing filter. The Recovery Coefficient (RC) of six spheres using three common Volume of Interest (VOI) methods (max, 3D-50% Isocontour, and peak) were calculated. Moreover, SUV(max), SUV(mean), and SUV(peak) and volumetric indices, such as metabolic tumor volume (MTV), volume recovery coefficient (VRC), and total lesion glycolysis (TLG) were measured. RC(max), RC(50%,) and RC(peak) as a function of sphere size were plotted in all reconstruction methods considering different SBRs. The data could be noticeable for standardization and optimization of quantitative metrics in PET imaging.