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The effect of parathyroid hormone on osteogenesis is mediated partly by osteolectin
We previously described a new osteogenic growth factor, osteolectin/Clec11a, which is required for the maintenance of skeletal bone mass during adulthood. Osteolectin binds to Integrin α11 (Itga11), promoting Wnt pathway activation and osteogenic differentiation by leptin receptor(+) (LepR(+)) strom...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237660/ https://www.ncbi.nlm.nih.gov/pubmed/34140410 http://dx.doi.org/10.1073/pnas.2026176118 |