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The effect of parathyroid hormone on osteogenesis is mediated partly by osteolectin

We previously described a new osteogenic growth factor, osteolectin/Clec11a, which is required for the maintenance of skeletal bone mass during adulthood. Osteolectin binds to Integrin α11 (Itga11), promoting Wnt pathway activation and osteogenic differentiation by leptin receptor(+) (LepR(+)) strom...

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Detalles Bibliográficos
Autores principales:	Zhang, Jingzhu, Cohen, Adi, Shen, Bo, Du, Liming, Tasdogan, Alpaslan, Zhao, Zhiyu, Shane, Elizabeth J., Morrison, Sean J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237660/ https://www.ncbi.nlm.nih.gov/pubmed/34140410 http://dx.doi.org/10.1073/pnas.2026176118

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