Oncolytic parainfluenza virus combines with NK cells to mediate killing of infected and non-infected lung cancer cells within 3D spheroids: role of type I and type III interferon signaling

BACKGROUND: There is intense interest in developing novel oncolytic viruses, which can be used in cancer therapies along with immune cells such as natural killer (NK) cells. We have previously developed a particle-based method for in vitro expansion of highly cytotoxic human NK cells (PM21-NK cells)...

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Detalles Bibliográficos
Autores principales: Varudkar, Namita, Oyer, Jeremiah L, Copik, Alicja, Parks, Griffith D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237729/
https://www.ncbi.nlm.nih.gov/pubmed/34172515
http://dx.doi.org/10.1136/jitc-2021-002373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237729/
https://www.ncbi.nlm.nih.gov/pubmed/34172515
http://dx.doi.org/10.1136/jitc-2021-002373

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