Cargando…

The C-X-C Motif Chemokine Ligand 1 Sustains Breast Cancer Stem Cell Self-Renewal and Promotes Tumor Progression and Immune Escape Programs

Breast cancer (BC) mortality is mainly due to metastatic disease, which is primarily driven by cancer stem cells (CSC). The chemokine C-X-C motif ligand-1 (CXCL1) is involved in BC metastasis, but the question of whether it regulates breast cancer stem cell (BCSC) behavior is yet to be explored. Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ciummo, Stefania Livia, D’Antonio, Luigi, Sorrentino, Carlo, Fieni, Cristiano, Lanuti, Paola, Stassi, Giorgio, Todaro, Matilde, Di Carlo, Emma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237942/ https://www.ncbi.nlm.nih.gov/pubmed/34195201 http://dx.doi.org/10.3389/fcell.2021.689286

Ejemplares similares

Interleukin-30 feeds breast cancer stem cells via CXCL10 and IL23 autocrine loops and shapes immune contexture and host outcome
por: Sorrentino, Carlo, et al.
Publicado: (2021)

Colorectal Cancer-Associated Immune Exhaustion Involves T and B Lymphocytes and Conventional NK Cells and Correlates With a Shorter Overall Survival
por: Sorrentino, Carlo, et al.
Publicado: (2021)

Inactivation of interleukin-30 in colon cancer stem cells via CRISPR/Cas9 genome editing inhibits their oncogenicity and improves host survival
por: D'Antonio, Luigi, et al.
Publicado: (2023)

CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality
por: Sorrentino, Carlo, et al.
Publicado: (2022)

Hindering triple negative breast cancer progression by targeting endogenous interleukin‐30 requires IFNγ signaling
por: Sorrentino, Carlo, et al.
Publicado: (2021)

Identification of Therapeutic Targets and Prognostic Biomarkers Among Chemokine (C-C Motif) Ligands in the Liver Hepatocellular Carcinoma Microenvironment
por: Jiang, Zhongyi, et al.
Publicado: (2021)

Cytotoxic chemotherapy reduces T cell trafficking to the spleen by downregulating the expression of C-C motif chemokine ligand 21 and C-C motif chemokine ligand 19
por: Liu, Lina, et al.
Publicado: (2018)

Dephosphorylation of Caveolin-1 Controls C-X-C Motif Chemokine Ligand 10 Secretion in Mesenchymal Stem Cells to Regulate the Process of Wound Healing
por: Wang, Panpan, et al.
Publicado: (2021)

The Significance of Selected C-C Motif Chemokine Ligands in Colorectal Cancer Patients
por: Zajkowska, Monika, et al.
Publicado: (2022)

Plasma levels of monokine induced by interferon-gamma/chemokine (C-X-X motif) ligand 9, thymus and activation-regulated chemokine/chemokine (C-C motif) ligand 17 in children with Kawasaki disease
por: Feng, Siqi, et al.
Publicado: (2015)

Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival
por: Sorrentino, Carlo, et al.
Publicado: (2019)

Interaction between epidermal growth factor receptor and C-C motif chemokine receptor 2 in the ovulatory cascade
por: Conte, J. G., et al.
Publicado: (2023)

Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain
por: Selenica, Maj-Linda B, et al.
Publicado: (2013)

Role of chemokine C-C motif ligand-1 in acute and chronic pulmonary inflammations
por: Kishi, Hiroyuki, et al.
Publicado: (2016)

Vascular Stem/Progenitor Cell Migration Induced by Smooth Muscle Cell‐Derived Chemokine (C‐C Motif) Ligand 2 and Chemokine (C‐X‐C motif) Ligand 1 Contributes to Neointima Formation
por: Yu, Baoqi, et al.
Publicado: (2016)

Ethanol promoting the upregulation of C-X-C Motif Chemokine Ligand 1（CXCL1） and C-X-C Motif Chemokine Ligand 6（CXCL6） in models of early alcoholic liver disease
por: Jiang, Yao, et al.
Publicado: (2022)

Chemokine (C-X-C motif) ligand 1/chemokine (C-X-C motif) receptor 2 autocrine loop contributes to cellular proliferation, migration and apoptosis in cervical cancer
por: Sun, Jiping, et al.
Publicado: (2022)

Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma
por: Arnold, J M, et al.
Publicado: (2005)

Chemokine C-C Motif Ligand 4 Gene Polymorphisms Associated with Susceptibility to Rheumatoid Arthritis
por: Kuo, Shu-Jui, et al.
Publicado: (2018)

Role of Chemokine (C–X–C Motif) Ligand 10 (CXCL10) in Renal Diseases
por: Gao, Jie, et al.
Publicado: (2020)

Chemokine (C-C Motif) Ligand 8 and Tubulo-Interstitial Injury in Chronic Kidney Disease
por: Lee, Jangwook, et al.
Publicado: (2022)

Plasma Chemokine C-C Motif Ligand 2 as a Potential Biomarker for Prostate Cancer
por: Lund, Martin, et al.
Publicado: (2022)

Multifaceted Roles of Chemokine C-X-C Motif Ligand 7 in Inflammatory Diseases and Cancer
por: Wu, Qianmiao, et al.
Publicado: (2022)

C-C Motif Chemokine Ligand 5 (CCL5) Promotes Irradiation-Evoked Osteoclastogenesis
por: Wang, Jing, et al.
Publicado: (2023)

Chemokine C‐C motif ligand 21 synergized with programmed death‐ligand 1 blockade restrains tumor growth
por: Chen, Qiangda, et al.
Publicado: (2021)

C-C motif chemokine ligand 2/C-C receptor 2 is associated with glioma recurrence and poor survival
por: Yang, Qiuan, et al.
Publicado: (2021)

Chemokine (C-C Motif) Ligand 20, a Potential Biomarker for Graves' Disease, Is Regulated by Osteopontin
por: Li, Xiaoli, et al.
Publicado: (2013)

C-X-C Motif Chemokine Ligand 14 is a Unique Multifunctional Regulator of Tumor Progression
por: Yang, Xiao-Yan, et al.
Publicado: (2019)

Diagnostic and prognostic values of C-X-C motif chemokine ligand 3 in patients with colon cancer
por: Ruan, Guo-Tian, et al.
Publicado: (2019)

Gene Expression Profiles in Chemokine (C-C Motif) Ligand 21-Overexpressing Pancreatic Cancer Cells
por: Cui, Kai, et al.
Publicado: (2018)

Astrocytic C–X–C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity
por: Perez-Nievas, Beatriz G., et al.
Publicado: (2021)

Correlation of Serum Chemokine (C-C Motif) Ligand 21 and Heat Shock Protein 90 with Preeclampsia
por: Yang, Weina, et al.
Publicado: (2022)

Collagen content and C-X-C motif chemokine ligand 12 expression in neoplastic breast stroma
por: Ferreira, Cindy Juliane da Silva, et al.
Publicado: (2023)

A‐kinase interacting protein 1 might serve as a novel biomarker for worse prognosis through the interaction of chemokine (C‐X‐C motif) ligand 1/chemokine (C‐X‐C motif) ligand 2 in acute myeloid leukemia
por: Hao, Xiaohong, et al.
Publicado: (2019)

Loss of atypical chemokine receptor 4 facilitates C-C motif chemokine ligand 21-mediated tumor growth and invasion in nasopharyngeal carcinoma
por: Ju, Yunhe, et al.
Publicado: (2019)

Elevated signal transducers and activators of transcription 1 correlates with increased C-C motif chemokine ligand 2 and C-X-C motif chemokine 10 levels in peripheral blood of patients with systemic lupus erythematosus
por: Dominguez-Gutierrez, Paul R, et al.
Publicado: (2014)

The Role of Autophagy and the Chemokine (C-X-C Motif) Ligand 16 During Acute Lung Injury in Mice
por: Gao, Ye, et al.
Publicado: (2018)

MicroRNA-31 promotes chondrocyte proliferation by targeting C-X-C motif chemokine ligand 12
por: Dai, Yankun, et al.
Publicado: (2019)

Endonuclease V Regulates Atherosclerosis Through C‐C Motif Chemokine Ligand 2‐Mediated Monocyte Infiltration
por: Kong, Xiang Yi, et al.
Publicado: (2021)

C–X–C motif chemokine ligand 12: a potential therapeutic target in Duchenne muscular dystrophy
por: Chen, Jie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p53pfed8nrijahjp7s8bbn22em