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Drug distribution along the cochlea is strongly enhanced by low-frequency round window micro vibrations
The cochlea’s inaccessibility and complex nature provide significant challenges to delivering drugs and other agents uniformly, safely and efficiently, along the entire cochlear spiral. Large drug concentration gradients are formed along the cochlea when drugs are administered to the middle ear. Thi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238068/ https://www.ncbi.nlm.nih.gov/pubmed/34176371 http://dx.doi.org/10.1080/10717544.2021.1943059 |