Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations

Associations between exposures and outcomes reported in epidemiological studies are typically unadjusted for genetic confounding. We propose a two-stage approach for estimating the degree to which such observed associations can be explained by genetic confounding. First, we assess attenuation of exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Pingault, Jean-Baptiste, Rijsdijk, Frühling, Schoeler, Tabea, Choi, Shing Wan, Selzam, Saskia, Krapohl, Eva, O’Reilly, Paul F., Dudbridge, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238188/
https://www.ncbi.nlm.nih.gov/pubmed/34115765
http://dx.doi.org/10.1371/journal.pgen.1009590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238188/
https://www.ncbi.nlm.nih.gov/pubmed/34115765
http://dx.doi.org/10.1371/journal.pgen.1009590

Ejemplares similares