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Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations
Associations between exposures and outcomes reported in epidemiological studies are typically unadjusted for genetic confounding. We propose a two-stage approach for estimating the degree to which such observed associations can be explained by genetic confounding. First, we assess attenuation of exp...
Autores principales: | Pingault, Jean-Baptiste, Rijsdijk, Frühling, Schoeler, Tabea, Choi, Shing Wan, Selzam, Saskia, Krapohl, Eva, O’Reilly, Paul F., Dudbridge, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238188/ https://www.ncbi.nlm.nih.gov/pubmed/34115765 http://dx.doi.org/10.1371/journal.pgen.1009590 |
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