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Hydroxychloroquine (HCQ) decreases the benefit of anti-PD-1 immune checkpoint blockade in tumor immunotherapy
Immunotherapy using checkpoint blockade (ICB) with antibodies such as anti-PD-1 has revolutionised the treatment of many cancers. Despite its use to treat COVID-19 patients and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis, the effect of hydroxychloroquine (HCQ) o...
Autores principales: | Krueger, Janna, Santinon, Francois, Kazanova, Alexandra, Issa, Mark E., Larrivee, Bruno, Kremer, Richard, Milhalcioiu, Catalin, Rudd, Christopher E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238207/ https://www.ncbi.nlm.nih.gov/pubmed/34181666 http://dx.doi.org/10.1371/journal.pone.0251731 |
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