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Targeting super-enhancers reprograms glioblastoma central carbon metabolism

The concept that tumor cells demand a distinct form of metabolism was appreciated almost a century ago when the German biochemist Otto Warburg realized that tumor cells heavily utilize glucose and produce lactic acid while relatively reducing oxidative metabolism. How this phenomenon is orchestrated...

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Detalles Bibliográficos
Autores principales:	Nguyen, Trang T.T., Westhoff, Mike-Andrew, Karpel-Massler, Georg, Siegelin, Markus D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2021
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238252/ https://www.ncbi.nlm.nih.gov/pubmed/34194627 http://dx.doi.org/10.18632/oncotarget.27938

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