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SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION

OBJECTIVE: SARS-CoV-2 disease is a severe infection that has forced millions of patients to stay in ICU.(2) SARS-CoV-2 pneumonia appears to occur rapidly and is often associated with gastrointestinal disorders that compromise the patient ability to adequately feed, causing a severely malnourished an...

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Autores principales: Scarcella, M., Commissari, R., Cappanera, S., Sensi, E., Scimmi, M., Tiri, B., De Robertis, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238415/
http://dx.doi.org/10.1016/j.nut.2021.111317
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author Scarcella, M.
Commissari, R.
Cappanera, S.
Sensi, E.
Scimmi, M.
Tiri, B.
De Robertis, E.
author_facet Scarcella, M.
Commissari, R.
Cappanera, S.
Sensi, E.
Scimmi, M.
Tiri, B.
De Robertis, E.
author_sort Scarcella, M.
collection PubMed
description OBJECTIVE: SARS-CoV-2 disease is a severe infection that has forced millions of patients to stay in ICU.(2) SARS-CoV-2 pneumonia appears to occur rapidly and is often associated with gastrointestinal disorders that compromise the patient ability to adequately feed, causing a severely malnourished and sarcopenic status.(1) Our hypothesis is that a strategy, based on the use of whey protein, that guarantee a fast achievement of protein and caloric targets, can reduce the duration of ventilation and mortality. METHODS AND PROCEDURES: We studied and treated 32 COVID-19 patients from 9/3 to 30/4/2020. The following nutritional targets were followed in all patients ⁃ start of enteral nutrition within 24/48 hours ⁃ protein target> = 1.3 g / kg ⁃ Caloric target 20/25 kcal / kg ⁃ Use of enteral mixtures rich in whey protein ⁃ Daily monitoring of prealbumin RESULTS: We observed that the 95% of patients presented a significant increase in prealbumin values (figure1) All patients who achieved a prealbumin value > 20 during hospitalization in ICU had a lower mortality. When the protein target was achieved in 2/3 days the time under mechanical ventilation was reduced ( figure 2-3) CONCLUSION: Although the data are hindered by the small number of patients, in our experience an adequate nutritional support that guarantees a rapid achievement of protein target, reduces ventilation time and mortality.
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spelling pubmed-82384152021-06-29 SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION Scarcella, M. Commissari, R. Cappanera, S. Sensi, E. Scimmi, M. Tiri, B. De Robertis, E. Nutrition 3 - Abstract 16 OBJECTIVE: SARS-CoV-2 disease is a severe infection that has forced millions of patients to stay in ICU.(2) SARS-CoV-2 pneumonia appears to occur rapidly and is often associated with gastrointestinal disorders that compromise the patient ability to adequately feed, causing a severely malnourished and sarcopenic status.(1) Our hypothesis is that a strategy, based on the use of whey protein, that guarantee a fast achievement of protein and caloric targets, can reduce the duration of ventilation and mortality. METHODS AND PROCEDURES: We studied and treated 32 COVID-19 patients from 9/3 to 30/4/2020. The following nutritional targets were followed in all patients ⁃ start of enteral nutrition within 24/48 hours ⁃ protein target> = 1.3 g / kg ⁃ Caloric target 20/25 kcal / kg ⁃ Use of enteral mixtures rich in whey protein ⁃ Daily monitoring of prealbumin RESULTS: We observed that the 95% of patients presented a significant increase in prealbumin values (figure1) All patients who achieved a prealbumin value > 20 during hospitalization in ICU had a lower mortality. When the protein target was achieved in 2/3 days the time under mechanical ventilation was reduced ( figure 2-3) CONCLUSION: Although the data are hindered by the small number of patients, in our experience an adequate nutritional support that guarantees a rapid achievement of protein target, reduces ventilation time and mortality. Published by Elsevier Inc. 2021-08 2021-06-28 /pmc/articles/PMC8238415/ http://dx.doi.org/10.1016/j.nut.2021.111317 Text en Copyright © 2021 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle 3 - Abstract 16
Scarcella, M.
Commissari, R.
Cappanera, S.
Sensi, E.
Scimmi, M.
Tiri, B.
De Robertis, E.
SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION
title SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION
title_full SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION
title_fullStr SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION
title_full_unstemmed SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION
title_short SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION
title_sort sars-cov2 critically ill pazients: focus on nutrition
topic 3 - Abstract 16
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238415/
http://dx.doi.org/10.1016/j.nut.2021.111317
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