Cargando…
SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION
OBJECTIVE: SARS-CoV-2 disease is a severe infection that has forced millions of patients to stay in ICU.(2) SARS-CoV-2 pneumonia appears to occur rapidly and is often associated with gastrointestinal disorders that compromise the patient ability to adequately feed, causing a severely malnourished an...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238415/ http://dx.doi.org/10.1016/j.nut.2021.111317 |
_version_ | 1783714898827542528 |
---|---|
author | Scarcella, M. Commissari, R. Cappanera, S. Sensi, E. Scimmi, M. Tiri, B. De Robertis, E. |
author_facet | Scarcella, M. Commissari, R. Cappanera, S. Sensi, E. Scimmi, M. Tiri, B. De Robertis, E. |
author_sort | Scarcella, M. |
collection | PubMed |
description | OBJECTIVE: SARS-CoV-2 disease is a severe infection that has forced millions of patients to stay in ICU.(2) SARS-CoV-2 pneumonia appears to occur rapidly and is often associated with gastrointestinal disorders that compromise the patient ability to adequately feed, causing a severely malnourished and sarcopenic status.(1) Our hypothesis is that a strategy, based on the use of whey protein, that guarantee a fast achievement of protein and caloric targets, can reduce the duration of ventilation and mortality. METHODS AND PROCEDURES: We studied and treated 32 COVID-19 patients from 9/3 to 30/4/2020. The following nutritional targets were followed in all patients ⁃ start of enteral nutrition within 24/48 hours ⁃ protein target> = 1.3 g / kg ⁃ Caloric target 20/25 kcal / kg ⁃ Use of enteral mixtures rich in whey protein ⁃ Daily monitoring of prealbumin RESULTS: We observed that the 95% of patients presented a significant increase in prealbumin values (figure1) All patients who achieved a prealbumin value > 20 during hospitalization in ICU had a lower mortality. When the protein target was achieved in 2/3 days the time under mechanical ventilation was reduced ( figure 2-3) CONCLUSION: Although the data are hindered by the small number of patients, in our experience an adequate nutritional support that guarantees a rapid achievement of protein target, reduces ventilation time and mortality. |
format | Online Article Text |
id | pubmed-8238415 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82384152021-06-29 SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION Scarcella, M. Commissari, R. Cappanera, S. Sensi, E. Scimmi, M. Tiri, B. De Robertis, E. Nutrition 3 - Abstract 16 OBJECTIVE: SARS-CoV-2 disease is a severe infection that has forced millions of patients to stay in ICU.(2) SARS-CoV-2 pneumonia appears to occur rapidly and is often associated with gastrointestinal disorders that compromise the patient ability to adequately feed, causing a severely malnourished and sarcopenic status.(1) Our hypothesis is that a strategy, based on the use of whey protein, that guarantee a fast achievement of protein and caloric targets, can reduce the duration of ventilation and mortality. METHODS AND PROCEDURES: We studied and treated 32 COVID-19 patients from 9/3 to 30/4/2020. The following nutritional targets were followed in all patients ⁃ start of enteral nutrition within 24/48 hours ⁃ protein target> = 1.3 g / kg ⁃ Caloric target 20/25 kcal / kg ⁃ Use of enteral mixtures rich in whey protein ⁃ Daily monitoring of prealbumin RESULTS: We observed that the 95% of patients presented a significant increase in prealbumin values (figure1) All patients who achieved a prealbumin value > 20 during hospitalization in ICU had a lower mortality. When the protein target was achieved in 2/3 days the time under mechanical ventilation was reduced ( figure 2-3) CONCLUSION: Although the data are hindered by the small number of patients, in our experience an adequate nutritional support that guarantees a rapid achievement of protein target, reduces ventilation time and mortality. Published by Elsevier Inc. 2021-08 2021-06-28 /pmc/articles/PMC8238415/ http://dx.doi.org/10.1016/j.nut.2021.111317 Text en Copyright © 2021 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | 3 - Abstract 16 Scarcella, M. Commissari, R. Cappanera, S. Sensi, E. Scimmi, M. Tiri, B. De Robertis, E. SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION |
title | SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION |
title_full | SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION |
title_fullStr | SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION |
title_full_unstemmed | SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION |
title_short | SARS-COV2 CRITICALLY ILL PAZIENTS: FOCUS ON NUTRITION |
title_sort | sars-cov2 critically ill pazients: focus on nutrition |
topic | 3 - Abstract 16 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238415/ http://dx.doi.org/10.1016/j.nut.2021.111317 |
work_keys_str_mv | AT scarcellam sarscov2criticallyillpazientsfocusonnutrition AT commissarir sarscov2criticallyillpazientsfocusonnutrition AT cappaneras sarscov2criticallyillpazientsfocusonnutrition AT sensie sarscov2criticallyillpazientsfocusonnutrition AT scimmim sarscov2criticallyillpazientsfocusonnutrition AT tirib sarscov2criticallyillpazientsfocusonnutrition AT derobertise sarscov2criticallyillpazientsfocusonnutrition |