Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

Germ granules are protein-RNA condensates that segregate with the embryonic germline. In Caenorhabditis elegans embryos, germ (P) granule assembly requires MEG-3, an intrinsically disordered protein that forms RNA-rich condensates on the surface of PGL condensates at the core of P granules. MEG-3 is...

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Detalles Bibliográficos
Autores principales: Schmidt, Helen, Putnam, Andrea, Rasoloson, Dominique, Seydoux, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238508/
https://www.ncbi.nlm.nih.gov/pubmed/34106046
http://dx.doi.org/10.7554/eLife.63698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238508/
https://www.ncbi.nlm.nih.gov/pubmed/34106046
http://dx.doi.org/10.7554/eLife.63698

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