Cargando…

Resveratrol Prevents Right Ventricle Dysfunction, Calcium Mishandling, and Energetic Failure via SIRT3 Stimulation in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vessel remodeling; however, its severity and impact on survival depend on right ventricular (RV) failure. Resveratrol (RES), a polyphenol found in red wine, exhibits cardioprotective effects on RV dysfunction in PAH. However, most l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bernal-Ramírez, Judith, Silva-Platas, Christian, Jerjes-Sánchez, Carlos, Ramos-González, Martín R., Vázquez-Garza, Eduardo, Chapoy-Villanueva, Héctor, Ramírez-Rivera, Alicia, Zarain-Herzberg, Ángel, García, Noemi, García-Rivas, Gerardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238598/ https://www.ncbi.nlm.nih.gov/pubmed/34239697 http://dx.doi.org/10.1155/2021/9912434

Ejemplares similares

Resveratrol Prevents Right Ventricle Remodeling and Dysfunction in Monocrotaline-Induced Pulmonary Arterial Hypertension with a Limited Improvement in the Lung Vasculature
por: Vázquez-Garza, Eduardo, et al.
Publicado: (2020)

Exploring Functional Differences between the Right and Left Ventricles to Better Understand Right Ventricular Dysfunction
por: Bernal-Ramirez, Judith, et al.
Publicado: (2021)

Small Interfering RNA Targeting Mitochondrial Calcium Uniporter Improves Cardiomyocyte Cell Viability in Hypoxia/Reoxygenation Injury by Reducing Calcium Overload
por: Oropeza-Almazán, Yuriana, et al.
Publicado: (2017)

Ex Vivo Cardiotoxicity of Antineoplastic Casiopeinas Is Mediated through Energetic Dysfunction and Triggered Mitochondrial-Dependent Apoptosis
por: Silva-Platas, Christian, et al.
Publicado: (2018)

Changes in the Stoichiometry of Uniplex Decrease Mitochondrial Calcium Overload and Contribute to Tolerance of Cardiac Ischemia/Reperfusion Injury in Hypothyroidism
por: Chapoy-Villanueva, Héctor, et al.
Publicado: (2019)

Partial Genetic Deletion of Klotho Aggravates Cardiac Calcium Mishandling in Acute Kidney Injury
por: González-Lafuente, Laura, et al.
Publicado: (2023)

Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats
por: Fernández-Miranda, Gaudencio, et al.
Publicado: (2019)

TRPC Channels: Dysregulation and Ca(2+) Mishandling in Ischemic Heart Disease
por: Falcón, Débora, et al.
Publicado: (2020)

EMA’s mishandling of an investigation into suspected serious neurological harms of HPV vaccines
por: Gøtzsche, Peter C, et al.
Publicado: (2022)

Microbial Competition of Rhodotorula mucilaginosa UANL-001L and E. coli increase biosynthesis of Non-Toxic Exopolysaccharide with Applications as a Wide-Spectrum Antimicrobial
por: Vazquez-Rodriguez, Augusto, et al.
Publicado: (2018)

Unilateral Acute Renal Ischemia-Reperfusion Injury Induces Cardiac Dysfunction through Intracellular Calcium Mishandling
por: Junho, Carolina Victoria Cruz, et al.
Publicado: (2022)

Stress-driven cardiac calcium mishandling via a kinase-to-kinase crosstalk
por: McKee, Charia, et al.
Publicado: (2021)

Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome
por: La Morgia, Chiara, et al.
Publicado: (2020)

Ca(2+) mishandling and mitochondrial dysfunction: a converging road to prediabetic and diabetic cardiomyopathy
por: Jaquenod De Giusti, Carolina, et al.
Publicado: (2022)

Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer’s disease
por: Mustaly-Kalimi, Sarah, et al.
Publicado: (2022)

Genetic Deletion of NOD1 Prevents Cardiac Ca(2+) Mishandling Induced by Experimental Chronic Kidney Disease
por: Gil-Fernández, Marta, et al.
Publicado: (2020)

Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice
por: Prins, Kurt W., et al.
Publicado: (2016)

Iron Overload, Oxidative Stress and Calcium Mishandling in Cardiomyocytes: Role of the Mitochondrial Permeability Transition Pore
por: Gordan, Richard, et al.
Publicado: (2020)

Sarco(endo)plasmic Reticulum Ca-ATPase-2 Gene: Structure and Transcriptional Regulation of the Human Gene
por: Zarain-Herzberg, Angel, et al.
Publicado: (2002)

Amorphous SiO2 nanoparticles promote cardiac dysfunction via the opening of the mitochondrial permeability transition pore in rat heart and human cardiomyocytes
por: Lozano, Omar, et al.
Publicado: (2020)

Nanoencapsulated Quercetin Improves Cardioprotection during Hypoxia-Reoxygenation Injury through Preservation of Mitochondrial Function
por: Lozano, Omar, et al.
Publicado: (2019)

Author Correction: Calcium mishandling in absence of primary mitochondrial dysfunction drives cellular pathology in Wolfram Syndrome
por: La Morgia, Chiara, et al.
Publicado: (2020)

Excessive salt consumption causes systemic calcium mishandling and worsens microarchitecture and strength of long bones in rats
por: Tiyasatkulkovit, Wacharaporn, et al.
Publicado: (2021)

Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
por: Grzeczka, Arkadiusz, et al.
Publicado: (2022)

Resveratrol-like Compounds as SIRT1 Activators
por: Ciccone, Lidia, et al.
Publicado: (2022)

Cardiomyocyte Na(+) and Ca(2+) mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors
por: Hegyi, Bence, et al.
Publicado: (2021)

Foreign Body Complications in Ears due to Mishandled Hearing Aid Fitting and Proposed Clinical Guidelines to Address the Complications
por: Cho, Eun-Hyun, et al.
Publicado: (2021)

The cardiac calsequestrin gene transcription is modulated at the promoter by NFAT and MEF-2 transcription factors
por: Estrada-Avilés, Rafael, et al.
Publicado: (2017)

Sirt1 activation by resveratrol is substrate sequence-selective
por: Lakshminarasimhan, Mahadevan, et al.
Publicado: (2013)

Activation of SIRT1 by Resveratrol requires lamin A
por: Liu, Baohua, et al.
Publicado: (2013)

Visualization and quantification of 4D blood flow distribution and energetics in the right ventricle
por: Carlhäll, Carl Johan, et al.
Publicado: (2011)

A systematic review of genetic mutations in pulmonary arterial hypertension
por: Garcia-Rivas, Gerardo, et al.
Publicado: (2017)

Molecular Cloning of a cDNA Encoding for Taenia solium TATA-Box Binding Protein 1 (TsTBP1) and Study of Its Interactions with the TATA-Box of Actin 5 and Typical 2-Cys Peroxiredoxin Genes
por: Rodríguez-Lima, Oscar, et al.
Publicado: (2015)

Radioprotective and Antioxidant Effect of Resveratrol in Hippocampus by Activating Sirt1
por: Li, Jianguo, et al.
Publicado: (2014)

Neuroprotective Mechanisms of Resveratrol in Alzheimer's Disease: Role of SIRT1
por: Gomes, Bruno Alexandre Quadros, et al.
Publicado: (2018)

Therapeutic Applications of Cannabinoids in Cardiomyopathy and Heart Failure
por: Garza-Cervantes, J. A., et al.
Publicado: (2020)

Proinflammatory Cytokines Are Soluble Mediators Linked with Ventricular Arrhythmias and Contractile Dysfunction in a Rat Model of Metabolic Syndrome
por: Fernández-Sada, Evaristo, et al.
Publicado: (2017)

Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation
por: Kilic Eren, Mehtap, et al.
Publicado: (2015)

Na(V)1.6 dysregulation within myocardial T-tubules by D96V calmodulin enhances proarrhythmic sodium and calcium mishandling
por: Tarasov, Mikhail, et al.
Publicado: (2023)

Resveratrol: brain effects on SIRT1, GPR50 and photoperiodic signaling
por: Leheste, Joerg R., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4scdai8cdn6eh67v9sie34ud02