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UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway

Vascular endothelial cell senescence is involved in human aging and age-related vascular disorders. Guidance receptor UNC5B is implicated in oxidative stress and angiogenesis. Nonetheless, little is known about the role of UNC5B in endothelial cell senescence. Here, we cultured primary human umbilic...

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Detalles Bibliográficos
Autores principales: Yang, Zhen, Li, Han, Luo, Pengcheng, Yan, Dan, Yang, Ni, Zhang, Yucong, Huang, Yi, Liu, Yu, Zhang, Le, Yan, Jinhua, Zhang, Cuntai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238614/
https://www.ncbi.nlm.nih.gov/pubmed/34239689
http://dx.doi.org/10.1155/2021/5546711