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Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication
The replication transcription complex (RTC) from the virus SARS-CoV-2 is responsible for recognizing and processing RNA for two principal purposes. The RTC copies viral RNA for propagation into new virus and for ribosomal transcription of viral proteins. To accomplish these activities, the RTC mecha...
Autores principales: | Wilamowski, Mateusz, Hammel, Michal, Leite, Wellington, Zhang, Qiu, Kim, Youngchang, Weiss, Kevin L., Jedrzejczak, Robert, Rosenberg, Daniel J., Fan, Yichong, Wower, Jacek, Bierma, Jan C., Sarker, Altaf H., Tsutakawa, Susan E., Pingali, Sai Venkatesh, O’Neill, Hugh M., Joachimiak, Andrzej, Hura, Greg L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238635/ https://www.ncbi.nlm.nih.gov/pubmed/34197805 http://dx.doi.org/10.1016/j.bpj.2021.06.006 |
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