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Transcription factor OTX2 silences the expression of cleavage embryo genes and transposable elements

Upon mammalian fertilization, zygotic genome activation (ZGA) and activation of transposable elements (TEs) occur in early embryos to establish totipotency and support embryogenesis. However, the molecular mechanisms controlling the expression of these genes in mammals remain poorly understood. The...

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Detalles Bibliográficos
Autores principales:	GUO, Shi-meng, MEI, Ning-hua, YANG, Jing, ZHOU, Li-quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238675/ https://www.ncbi.nlm.nih.gov/pubmed/33896883 http://dx.doi.org/10.1262/jrd.2021-007

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