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GHS-R suppression in adipose tissues protects against obesity and insulin resistance by regulating adipose angiogenesis and fibrosis

BACKGROUND/OBJECTIVES: Ghrelin is an orexigenic hormone that increases food intake, adiposity, and insulin resistance through its receptor Growth Hormone Secretagogue Receptor (GHS-R). We previously showed that ghrelin/GHS-R signaling has important roles in regulation of energy homeostasis, and glob...

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Detalles Bibliográficos
Autores principales: Lee, Jong Han, Fang, Chuo, Li, Xin, Wu, Chia Shan, Noh, Ji Yeon, Ye, Xiangcang, Chapkin, Robert S., Sun, Kai, Sun, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238886/
https://www.ncbi.nlm.nih.gov/pubmed/33903722
http://dx.doi.org/10.1038/s41366-021-00820-7