Predictable control of RNA lifetime using engineered degradation-tuning RNAs

The ability to tune RNA and gene expression dynamics is greatly needed for biotechnological applications. Native RNA stabilizers or engineered 5’ stability hairpins have been utilized to regulate transcript half-life to control recombinant protein expression. However, these methods have been mostly...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Ma, Duo, Wu, Fuqing, Standage-Beier, Kylie, Chen, Xingwen, Wu, Kaiyue, Green, Alexander A., Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238901/
https://www.ncbi.nlm.nih.gov/pubmed/34155402
http://dx.doi.org/10.1038/s41589-021-00816-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238901/
https://www.ncbi.nlm.nih.gov/pubmed/34155402
http://dx.doi.org/10.1038/s41589-021-00816-4

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