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Predictable control of RNA lifetime using engineered degradation-tuning RNAs
The ability to tune RNA and gene expression dynamics is greatly needed for biotechnological applications. Native RNA stabilizers or engineered 5’ stability hairpins have been utilized to regulate transcript half-life to control recombinant protein expression. However, these methods have been mostly...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238901/ https://www.ncbi.nlm.nih.gov/pubmed/34155402 http://dx.doi.org/10.1038/s41589-021-00816-4 |