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Porcine pancreatic ductal epithelial cells transformed with KRAS(G12D) and SV40T are tumorigenic

We describe our initial studies in the development of an orthotopic, genetically defined, large animal model of pancreatic cancer. Primary pancreatic epithelial cells were isolated from pancreatic duct of domestic pigs. A transformed cell line was generated from these primary cells with oncogenic KR...

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Detalles Bibliográficos
Autores principales:	Bailey, Katie L., Cartwright, Sara B., Patel, Neesha S., Remmers, Neeley, Lazenby, Audrey J., Hollingsworth, Michael A., Carlson, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238942/ https://www.ncbi.nlm.nih.gov/pubmed/34183736 http://dx.doi.org/10.1038/s41598-021-92852-2

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