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Spatial organization of FcγR and TLR2/1 on phagosome membranes differentially regulates their synergistic and inhibitory receptor crosstalk

Many innate immune receptors function collaboratively to detect and elicit immune responses to pathogens, but the physical mechanisms that govern the interaction and signaling crosstalk between the receptors are unclear. In this study, we report that the signaling crosstalk between Fc gamma receptor...

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Detalles Bibliográficos
Autores principales: Li, Wenqian, Li, Miao, Anthony, Stephen M., Yu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238967/
https://www.ncbi.nlm.nih.gov/pubmed/34183758
http://dx.doi.org/10.1038/s41598-021-92910-9