High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production

Coordination of RNA abundance and production rate with cell size has been observed in diverse organisms and cell populations. However, how cells achieve such ‘scaling’ of transcription with size is unknown. Here we describe a genome-wide siRNA screen to identify regulators of global RNA production r...

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Detalles Bibliográficos
Autores principales: Müller, Micha, Avar, Merve, Heinzer, Daniel, Emmenegger, Marc, Aguzzi, Adriano, Pelkmans, Lucas, Berry, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239010/
https://www.ncbi.nlm.nih.gov/pubmed/34183683
http://dx.doi.org/10.1038/s41597-021-00944-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239010/
https://www.ncbi.nlm.nih.gov/pubmed/34183683
http://dx.doi.org/10.1038/s41597-021-00944-5

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