Acute Kidney Injury in Pediatric Diabetic Kidney Disease

Diabetic kidney disease (DKD) is a common complication of type 1 and 2 diabetes and often presents during adolescence and young adulthood. Given the growing incidence of both type 1 and type 2 diabetes in children and adolescents, DKD represents a significant public health problem. Acute kidney inju...

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Autores principales: Piani, Federica, Reinicke, Trenton, Borghi, Claudio, Tommerdahl, Kalie L., Cara-Fuentes, Gabriel, Johnson, Richard J., Bjornstad, Petter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239177/
https://www.ncbi.nlm.nih.gov/pubmed/34211943
http://dx.doi.org/10.3389/fped.2021.668033
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author Piani, Federica
Reinicke, Trenton
Borghi, Claudio
Tommerdahl, Kalie L.
Cara-Fuentes, Gabriel
Johnson, Richard J.
Bjornstad, Petter
author_facet Piani, Federica
Reinicke, Trenton
Borghi, Claudio
Tommerdahl, Kalie L.
Cara-Fuentes, Gabriel
Johnson, Richard J.
Bjornstad, Petter
author_sort Piani, Federica
collection PubMed
description Diabetic kidney disease (DKD) is a common complication of type 1 and 2 diabetes and often presents during adolescence and young adulthood. Given the growing incidence of both type 1 and type 2 diabetes in children and adolescents, DKD represents a significant public health problem. Acute kidney injury (AKI) in youth with diabetes is strongly associated with risk of DKD development. This review will summarize the epidemiology and pathophysiology of AKI in children with diabetes, the relationship between AKI and DKD, and the potential therapeutic interventions. Finally, we will appraise the impact of the recent COVID-19 infection pandemic on AKI in children with diabetes.
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spelling pubmed-82391772021-06-30 Acute Kidney Injury in Pediatric Diabetic Kidney Disease Piani, Federica Reinicke, Trenton Borghi, Claudio Tommerdahl, Kalie L. Cara-Fuentes, Gabriel Johnson, Richard J. Bjornstad, Petter Front Pediatr Pediatrics Diabetic kidney disease (DKD) is a common complication of type 1 and 2 diabetes and often presents during adolescence and young adulthood. Given the growing incidence of both type 1 and type 2 diabetes in children and adolescents, DKD represents a significant public health problem. Acute kidney injury (AKI) in youth with diabetes is strongly associated with risk of DKD development. This review will summarize the epidemiology and pathophysiology of AKI in children with diabetes, the relationship between AKI and DKD, and the potential therapeutic interventions. Finally, we will appraise the impact of the recent COVID-19 infection pandemic on AKI in children with diabetes. Frontiers Media S.A. 2021-06-15 /pmc/articles/PMC8239177/ /pubmed/34211943 http://dx.doi.org/10.3389/fped.2021.668033 Text en Copyright © 2021 Piani, Reinicke, Borghi, Tommerdahl, Cara-Fuentes, Johnson and Bjornstad. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Piani, Federica
Reinicke, Trenton
Borghi, Claudio
Tommerdahl, Kalie L.
Cara-Fuentes, Gabriel
Johnson, Richard J.
Bjornstad, Petter
Acute Kidney Injury in Pediatric Diabetic Kidney Disease
title Acute Kidney Injury in Pediatric Diabetic Kidney Disease
title_full Acute Kidney Injury in Pediatric Diabetic Kidney Disease
title_fullStr Acute Kidney Injury in Pediatric Diabetic Kidney Disease
title_full_unstemmed Acute Kidney Injury in Pediatric Diabetic Kidney Disease
title_short Acute Kidney Injury in Pediatric Diabetic Kidney Disease
title_sort acute kidney injury in pediatric diabetic kidney disease
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239177/
https://www.ncbi.nlm.nih.gov/pubmed/34211943
http://dx.doi.org/10.3389/fped.2021.668033
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