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Dynamics of the SARS-CoV-2 nucleoprotein N-terminal domain triggers RNA duplex destabilization
The nucleocapsid (N) protein of betacoronaviruses is responsible for nucleocapsid assembly and other essential regulatory functions. The N protein N-terminal domain (N-NTD) interacts and melts the double-stranded transcriptional regulatory sequences (dsTRSs), regulating the discontinuous subgenome t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239202/ https://www.ncbi.nlm.nih.gov/pubmed/34197802 http://dx.doi.org/10.1016/j.bpj.2021.06.003 |