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Dynamics of the SARS-CoV-2 nucleoprotein N-terminal domain triggers RNA duplex destabilization

The nucleocapsid (N) protein of betacoronaviruses is responsible for nucleocapsid assembly and other essential regulatory functions. The N protein N-terminal domain (N-NTD) interacts and melts the double-stranded transcriptional regulatory sequences (dsTRSs), regulating the discontinuous subgenome t...

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Detalles Bibliográficos
Autores principales: Caruso, Ícaro P., Sanches, Karoline, Da Poian, Andrea T., Pinheiro, Anderson S., Almeida, Fabio C.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239202/
https://www.ncbi.nlm.nih.gov/pubmed/34197802
http://dx.doi.org/10.1016/j.bpj.2021.06.003