High-Density of FcγRIIIA(+) (CD16(+)) Tumor-Associated Neutrophils in Metastases Improves the Therapeutic Response of Cetuximab in Metastatic Colorectal Cancer Patients, Independently of the HLA-E/CD94-NKG2A Axis

Antibody-dependent cellular cytotoxicity (ADCC) in the anti-tumor effect of cetuximab in metastatic colorectal cancer (mCRC) is only based on the impact of FcγRIIIA (CD16) polymorphisms as predictive of therapeutic response. However, nature, density and therapeutic impact of FcγRIIIA(+) (CD16) effec...

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Detalles Bibliográficos
Autores principales: Denis Musquer, Marie, Jouand, Nicolas, Pere, Morgane, Lamer, Juliette Eugène, Bézieau, Stéphane, Matysiak, Tamara, Faroux, Roger, Caroli Bosc, François-Xavier, Rousselet, Marie-Christine, Leclair, François, Mosnier, Jean-François, Toquet, Claire, Gervois, Nadine, Bossard, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239306/
https://www.ncbi.nlm.nih.gov/pubmed/34211852
http://dx.doi.org/10.3389/fonc.2021.684478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239306/
https://www.ncbi.nlm.nih.gov/pubmed/34211852
http://dx.doi.org/10.3389/fonc.2021.684478

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