Cargando…

Osteoking Decelerates Cartilage Degeneration in DMM-Induced Osteoarthritic Mice Model Through TGF-β/smad-dependent Manner

Osteoarthritis (OA) is a common disease characterized by cartilage degeneration. In recent years much attention has been paid to Traditional Chinese Medicine (TCM) since its treatments have shown efficacy for ameliorating cartilage degradation with mild side effects. Osteoking is a TCM prescription...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ling, Houfu, Zeng, Qinghe, Ge, Qinwen, Chen, Jiali, Yuan, Wenhua, Xu, Rui, Shi, Zhenyu, Xia, Hanting, Hu, Songfeng, Jin, Hongting, Wang, Pinger, Tong, Peijian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239307/ https://www.ncbi.nlm.nih.gov/pubmed/34211396 http://dx.doi.org/10.3389/fphar.2021.678810

Ejemplares similares

Fractions of Shen-Sui-Tong-Zhi Formula Enhance Osteogenesis Via Activation of β-Catenin Signaling in Growth Plate Chondrocytes
por: Xu, Rui, et al.
Publicado: (2021)

Elucidation of the Underlying Mechanism of Gujian Oral Liquid Acting on Osteoarthritis through Network Pharmacology, Molecular Docking, and Experiment
por: Wu, Congzi, et al.
Publicado: (2022)

Yougui Pills Attenuate Cartilage Degeneration via Activation of TGF-β/Smad Signaling in Chondrocyte of Osteoarthritic Mouse Model
por: Zhang, Lei, et al.
Publicado: (2017)

Effects of OsteoKing on osteoporotic rabbits
por: DAI, LIFEN, et al.
Publicado: (2015)

Amygdalin Delays Cartilage Endplate Degeneration and Improves Intervertebral Disc Degeneration by Inhibiting NF-κB Signaling Pathway and Inflammatory Response
por: Zeng, Qinghe, et al.
Publicado: (2023)

Amygdalin Promotes Fracture Healing through TGF-β/Smad Signaling in Mesenchymal Stem Cells
por: Ying, Jun, et al.
Publicado: (2020)

Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice
por: Liao, Lifan, et al.
Publicado: (2017)

Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH
por: Xu, Huihui, et al.
Publicado: (2023)

N-Butanol Extract of Modified You-Gui-Yin Attenuates Osteoclastogenesis and Ameliorates Osteoporosis by Inhibiting RANKL-Mediated NF-κB Signaling
por: Zeng, Qinghe, et al.
Publicado: (2022)

Protein phosphatase PPM1A inhibition attenuates osteoarthritis via regulating TGF-β/Smad2 signaling in chondrocytes
por: Ge, Qinwen, et al.
Publicado: (2023)

Osteoking improves OP rat by enhancing HSP90-β expression
por: Sun, Yan, et al.
Publicado: (2020)

Col9a2 gene deletion accelerates the degeneration of intervertebral discs
por: Xu, Huihui, et al.
Publicado: (2022)

Early Changes of Articular Cartilage and Subchondral Bone in The DMM Mouse Model of Osteoarthritis
por: Fang, Hang, et al.
Publicado: (2018)

Bushenhuoxue formula attenuates cartilage degeneration in an osteoarthritic mouse model through TGF-β/MMP13 signaling
por: Wang, Ping-er, et al.
Publicado: (2018)

Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice
por: Li, Guoqing, et al.
Publicado: (2022)

Bushenhuoxue Formula Facilitates Articular Cartilage Repair and Attenuates Matrix Degradation by Activation of TGF-β Signaling Pathway
por: Dong, Rui, et al.
Publicado: (2018)

Chondroprotective Mechanism of Eucommia ulmoides Oliv.-Glycyrrhiza uralensis Fisch. Couplet Medicines in Knee Osteoarthritis via Experimental Study and Network Pharmacology Analysis
por: Wang, Pinger, et al.
Publicado: (2023)

Defining disease progression in Chinese mainland people: Association between bone mineral density and knee osteoarthritis
por: Fang, Liang, et al.
Publicado: (2020)

Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway
por: Aref-Eshghi, Erfan, et al.
Publicado: (2015)

The Role of Autophagy in Osteoarthritic Cartilage
por: Kao, Wei-Chun, et al.
Publicado: (2022)

A thank you to DMM's peer reviewers
por: Hackett, Rachel
Publicado: (2019)

DMM Prize 2018 winner: Wenqing Zhou
por: Justice, Monica J.
Publicado: (2019)

Effect of Osteoking on the osteogenic and adipogenic differentiation potential of rat bone marrow mesenchymal stem cells in vitro
por: Yu, Congtao, et al.
Publicado: (2019)

Genome‐wide microRNA screening reveals miR‐582‐5p as a mesenchymal stem cell‐specific microRNA in subchondral bone of the human knee joint
por: Wang, Pinger, et al.
Publicado: (2019)

Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage
por: Koike, Masato, et al.
Publicado: (2018)

Integrated Strategy of Network Pharmacological Prediction and Experimental Validation Elucidate Possible Mechanism of Bu-Yang Herbs in Treating Postmenopausal Osteoporosis via ESR1
por: Xia, Hanting, et al.
Publicado: (2021)

The role of aggrecan in normal and osteoarthritic cartilage
por: Roughley, Peter J, et al.
Publicado: (2014)

A brief review of peer review in DMM in 2019
por: Hackett, Rachel
Publicado: (2020)

A Case of Typhoid Pneumonia Cured with Hyos.(DMM)
por: Kimball, Samuel A.
Publicado: (1893)

Impactful disease research: a DMM year in review
por: Hackett, Rachel, et al.
Publicado: (2023)

Lipid Transport and Metabolism in Healthy and Osteoarthritic Cartilage
por: Villalvilla, Amanda, et al.
Publicado: (2013)

Heparan sulfate functions are altered in the osteoarthritic cartilage
por: Shamdani, Sara, et al.
Publicado: (2020)

DMM Outstanding Paper Prize 2019 winner: Alessandro Bailetti
por: Hackett, Rachel
Publicado: (2020)

DMM Outstanding Paper Prize 2020 winner: Sarah Colijn
por: Hackett, Rachel
Publicado: (2021)

DMM Outstanding Paper Prize 2021 winner: Daniel Bronder
por: Hackett, Rachel
Publicado: (2022)

TGF‐β/Smad2 signalling regulates enchondral bone formation of Gli1(+) periosteal cells during fracture healing
por: Xia, Chenjie, et al.
Publicado: (2020)

Oral Administration of Bovine Milk-Derived Extracellular Vesicles Attenuates Cartilage Degeneration via Modulating Gut Microbiota in DMM-Induced Mice
por: Liu, Qiqi, et al.
Publicado: (2023)

MRI-based hip cartilage measures in osteoarthritic and non-osteoarthritic individuals: a systematic review
por: Aguilar, Hector N, et al.
Publicado: (2017)

Cartilage repair in osteoarthritic patients: utopia or real opportunity?
por: Henrotin, Yves, et al.
Publicado: (2009)

Arthroscopic cartilage regeneration facilitating procedure for osteoarthritic knee
por: Lyu, Shaw-Ruey, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_85sgm5pallm65gvotbvkccqafb