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miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease

Parkinson’s disease (PD) is mainly driven by dopaminergic neuronal degeneration in the substantia nigra pars compacta accompanied by chronic neuroinflammation. Despite being mainly sporadic, approximately 10% of all cases are defined as heritable forms of PD, with mutations in the leucine-rich repea...

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Detalles Bibliográficos
Autores principales: Oliveira, Sara R., Dionísio, Pedro A., Gaspar, Maria M., Correia Guedes, Leonor, Coelho, Miguel, Rosa, Mário M., Ferreira, Joaquim J., Amaral, Joana D., Rodrigues, Cecília M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239393/
https://www.ncbi.nlm.nih.gov/pubmed/34211970
http://dx.doi.org/10.3389/fcell.2021.661461

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