Cargando…
miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease
Parkinson’s disease (PD) is mainly driven by dopaminergic neuronal degeneration in the substantia nigra pars compacta accompanied by chronic neuroinflammation. Despite being mainly sporadic, approximately 10% of all cases are defined as heritable forms of PD, with mutations in the leucine-rich repea...
Autores principales: | Oliveira, Sara R., Dionísio, Pedro A., Gaspar, Maria M., Correia Guedes, Leonor, Coelho, Miguel, Rosa, Mário M., Ferreira, Joaquim J., Amaral, Joana D., Rodrigues, Cecília M. P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239393/ https://www.ncbi.nlm.nih.gov/pubmed/34211970 http://dx.doi.org/10.3389/fcell.2021.661461 |
Ejemplares similares
-
Circulating Inflammatory miRNAs Associated with Parkinson’s Disease Pathophysiology
por: Oliveira, Sara R., et al.
Publicado: (2020) -
A Conserved Role for LRRK2 and Roco Proteins in the Regulation of Mitochondrial Activity
por: Rosenbusch, Katharina E., et al.
Publicado: (2021) -
Role of LrrkA in the Control of Phagocytosis and Cell Motility in Dictyostelium discoideum
por: Bodinier, Romain, et al.
Publicado: (2021) -
Pharmacological rescue of impaired mitophagy in Parkinson’s disease-related LRRK2 G2019S knock-in mice
por: Singh, Francois, et al.
Publicado: (2021) -
Fish Models of Induced Osteoporosis
por: Rosa, Joana T., et al.
Publicado: (2021)