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Mito-Tempo suppresses autophagic flux via the PI3K/Akt/mTOR signaling pathway in neuroblastoma SH-SY5Y cells

The generation of excessive mitochondrial reactive oxygen species (mtROS) is associated with glutamate-stimulated neurotoxicity and pathogenesis of Alzheimer's disease (AD). Impaired mitochondrial function is accompanied with oxidative stress that is a significant contributor to initiate autoph...

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Detalles Bibliográficos
Autores principales:	Mukem, Sirirak, Thongbuakaew, Tipsuda, Khornchatri, Kanjana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239474/ https://www.ncbi.nlm.nih.gov/pubmed/34195421 http://dx.doi.org/10.1016/j.heliyon.2021.e07310

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