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The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells

Collagen-derived hydroxyproline (Hyp)-containing peptides have a variety of biological effects on cells. These bioactive collagen peptides are locally generated by the degradation of endogenous collagen in response to injury. However, no comprehensive study has yet explored the functional links betw...

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Detalles Bibliográficos
Autores principales: Ide, Kentaro, Takahashi, Sanai, Sakai, Keiko, Taga, Yuki, Ueno, Tomonori, Dickens, David, Jenkins, Rosalind, Falciani, Francesco, Sasaki, Takako, Ooi, Kazuhiro, Kawashiri, Shuichi, Mizuno, Kazunori, Hattori, Shunji, Sakai, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239475/
https://www.ncbi.nlm.nih.gov/pubmed/34029590
http://dx.doi.org/10.1016/j.jbc.2021.100819