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Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates

Primary pulmonary extra‐nodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma), also known as bronchus‐associated lymphoid tissue (BALT lymphoma), is the most common primary pulmonary lymphoma but is rare (<1%) among all non‐Hodgkin lymphomas and among pulmonary neoplas...

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Detalles Bibliográficos
Autores principales: Smyth, Robert, Sloan, John Mark, Burks, Eric, Hawkins, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239556/
https://www.ncbi.nlm.nih.gov/pubmed/34221408
http://dx.doi.org/10.1002/rcr2.806
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author Smyth, Robert
Sloan, John Mark
Burks, Eric
Hawkins, Finn
author_facet Smyth, Robert
Sloan, John Mark
Burks, Eric
Hawkins, Finn
author_sort Smyth, Robert
collection PubMed
description Primary pulmonary extra‐nodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma), also known as bronchus‐associated lymphoid tissue (BALT lymphoma), is the most common primary pulmonary lymphoma but is rare (<1%) among all non‐Hodgkin lymphomas and among pulmonary neoplasms in general. We herein report the case of a 59‐year‐old male who presented with stable exertional dyspnoea and persistent lung infiltrates who was referred to our hospital for further assessment. A computed tomography (CT)‐guided core biopsy was performed showing a dense lymphoid infiltrate, with further testing revealing the diagnosis of pulmonary MALT lymphoma. This uncommon lung tumour is usually seen in older adults and typically associated with a relatively indolent course. Rituximab, an anti‐CD20 antibody, has been shown to be effective in up to 70% of cases.
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spelling pubmed-82395562021-07-02 Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates Smyth, Robert Sloan, John Mark Burks, Eric Hawkins, Finn Respirol Case Rep Case Reports Primary pulmonary extra‐nodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma), also known as bronchus‐associated lymphoid tissue (BALT lymphoma), is the most common primary pulmonary lymphoma but is rare (<1%) among all non‐Hodgkin lymphomas and among pulmonary neoplasms in general. We herein report the case of a 59‐year‐old male who presented with stable exertional dyspnoea and persistent lung infiltrates who was referred to our hospital for further assessment. A computed tomography (CT)‐guided core biopsy was performed showing a dense lymphoid infiltrate, with further testing revealing the diagnosis of pulmonary MALT lymphoma. This uncommon lung tumour is usually seen in older adults and typically associated with a relatively indolent course. Rituximab, an anti‐CD20 antibody, has been shown to be effective in up to 70% of cases. John Wiley & Sons, Ltd 2021-06-29 /pmc/articles/PMC8239556/ /pubmed/34221408 http://dx.doi.org/10.1002/rcr2.806 Text en © 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Smyth, Robert
Sloan, John Mark
Burks, Eric
Hawkins, Finn
Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
title Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
title_full Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
title_fullStr Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
title_full_unstemmed Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
title_short Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
title_sort primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239556/
https://www.ncbi.nlm.nih.gov/pubmed/34221408
http://dx.doi.org/10.1002/rcr2.806
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