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Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates
Primary pulmonary extra‐nodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma), also known as bronchus‐associated lymphoid tissue (BALT lymphoma), is the most common primary pulmonary lymphoma but is rare (<1%) among all non‐Hodgkin lymphomas and among pulmonary neoplas...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239556/ https://www.ncbi.nlm.nih.gov/pubmed/34221408 http://dx.doi.org/10.1002/rcr2.806 |
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author | Smyth, Robert Sloan, John Mark Burks, Eric Hawkins, Finn |
author_facet | Smyth, Robert Sloan, John Mark Burks, Eric Hawkins, Finn |
author_sort | Smyth, Robert |
collection | PubMed |
description | Primary pulmonary extra‐nodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma), also known as bronchus‐associated lymphoid tissue (BALT lymphoma), is the most common primary pulmonary lymphoma but is rare (<1%) among all non‐Hodgkin lymphomas and among pulmonary neoplasms in general. We herein report the case of a 59‐year‐old male who presented with stable exertional dyspnoea and persistent lung infiltrates who was referred to our hospital for further assessment. A computed tomography (CT)‐guided core biopsy was performed showing a dense lymphoid infiltrate, with further testing revealing the diagnosis of pulmonary MALT lymphoma. This uncommon lung tumour is usually seen in older adults and typically associated with a relatively indolent course. Rituximab, an anti‐CD20 antibody, has been shown to be effective in up to 70% of cases. |
format | Online Article Text |
id | pubmed-8239556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-82395562021-07-02 Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates Smyth, Robert Sloan, John Mark Burks, Eric Hawkins, Finn Respirol Case Rep Case Reports Primary pulmonary extra‐nodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma), also known as bronchus‐associated lymphoid tissue (BALT lymphoma), is the most common primary pulmonary lymphoma but is rare (<1%) among all non‐Hodgkin lymphomas and among pulmonary neoplasms in general. We herein report the case of a 59‐year‐old male who presented with stable exertional dyspnoea and persistent lung infiltrates who was referred to our hospital for further assessment. A computed tomography (CT)‐guided core biopsy was performed showing a dense lymphoid infiltrate, with further testing revealing the diagnosis of pulmonary MALT lymphoma. This uncommon lung tumour is usually seen in older adults and typically associated with a relatively indolent course. Rituximab, an anti‐CD20 antibody, has been shown to be effective in up to 70% of cases. John Wiley & Sons, Ltd 2021-06-29 /pmc/articles/PMC8239556/ /pubmed/34221408 http://dx.doi.org/10.1002/rcr2.806 Text en © 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Smyth, Robert Sloan, John Mark Burks, Eric Hawkins, Finn Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates |
title | Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates |
title_full | Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates |
title_fullStr | Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates |
title_full_unstemmed | Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates |
title_short | Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates |
title_sort | primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239556/ https://www.ncbi.nlm.nih.gov/pubmed/34221408 http://dx.doi.org/10.1002/rcr2.806 |
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