Cargando…

Association Between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID‐19: An Observational Multicenter Study

Several medications commonly used for a number of medical conditions share a property of functional inhibition of acid sphingomyelinase (ASM), or FIASMA. Preclinical and clinical evidence suggest that the ASM/ceramide system may be central to severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hoertel, Nicolas, Sánchez‐Rico, Marina, Gulbins, Erich, Kornhuber, Johannes, Carpinteiro, Alexander, Lenze, Eric J., Reiersen, Angela M., Abellán, Miriam, de la Muela, Pedro, Vernet, Raphaël, Blanco, Carlos, Cougoule, Céline, Beeker, Nathanaël, Neuraz, Antoine, Gorwood, Philip, Alvarado, Jesús M., Meneton, Pierre, Limosin, Frédéric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239599/ https://www.ncbi.nlm.nih.gov/pubmed/34050932 http://dx.doi.org/10.1002/cpt.2317

Ejemplares similares

Association between FIASMA psychotropic medications and reduced risk of intubation or death in individuals with psychiatric disorders hospitalized for severe COVID-19: an observational multicenter study
por: Hoertel, Nicolas, et al.
Publicado: (2022)

Antidepressant Use and Its Association with 28-Day Mortality in Inpatients with SARS-CoV-2: Support for the FIASMA Model against COVID-19
por: Hoertel, Nicolas, et al.
Publicado: (2022)

Antidepressant Use and Its Association with 28-Day Mortality in Inpatients with SARS-CoV-2: Support for the FIASMA Model against COVID-19
por: Hoertel, N., et al.
Publicado: (2023)

Risk of Death in Individuals Hospitalized for COVID-19 With and Without Psychiatric Disorders: An Observational Multicenter Study in France
por: Hoertel, Nicolas, et al.
Publicado: (2022)

Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms
por: Hoertel, Nicolas, et al.
Publicado: (2021)

Association between benzodiazepine receptor agonist use and mortality in patients hospitalised for COVID-19: a multicentre observational study
por: Hoertel, N., et al.
Publicado: (2022)

Comorbid medical conditions are a key factor to understand the relationship between psychiatric disorders and COVID-19-related mortality: Results from 49,089 COVID-19 inpatients
por: Hoertel, Nicolas, et al.
Publicado: (2021)

Medications Modulating the Acid Sphingomyelinase/Ceramide System and 28-Day Mortality among Patients with SARS-CoV-2: An Observational Study
por: Hoertel, Nicolas, et al.
Publicado: (2023)

Hydroxyzine Use and Mortality in Patients Hospitalized for COVID-19: A Multicenter Observational Study
por: Sánchez-Rico, Marina, et al.
Publicado: (2021)

Observational Study of Chlorpromazine in Hospitalized Patients with COVID-19
por: Hoertel, Nicolas, et al.
Publicado: (2021)

Observational study of haloperidol in hospitalized patients with COVID-19
por: Hoertel, Nicolas, et al.
Publicado: (2021)

The acid sphingomyelinase/ceramide system in COVID-19
por: Kornhuber, Johannes, et al.
Publicado: (2021)

Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model
por: Péricat, David, et al.
Publicado: (2022)

Retirement age does not modify the association of prior working conditions with self-rated health and mortality in retirees: results from a prospective study of retired French workers
por: Hoertel, Nicolas, et al.
Publicado: (2022)

Respective Mediating Effects of Social Position and Work Environment on the Incidence of Common Cardiovascular Risk Factors
por: Hoertel, Nicolas, et al.
Publicado: (2022)

Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells
por: Carpinteiro, Alexander, et al.
Publicado: (2021)

Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model
por: Péricat, D., et al.
Publicado: (2023)

Prevalence of Subthreshold Hypomania and Impact on Internal Validity of RCTs for Major Depressive Disorder: Results from a National Epidemiological Sample
por: Hoertel, Nicolas, et al.
Publicado: (2013)

Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells
por: Becker, Katrin Anne, et al.
Publicado: (2021)

Association between antidepressant use and ED or hospital visits in outpatients with SARS-CoV-2
por: Fritz, Bradley A., et al.
Publicado: (2022)

Update on Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) in SARS-CoV-2 Infection
por: Loas, Gwenolé, et al.
Publicado: (2021)

Mortality in older adults with severe mental illness: the role of metabolic syndrome and its components
por: Abou Kassm, S., et al.
Publicado: (2023)

Comorbidity patterns and mortality among hospitalized patients with psychiatric disorders and COVID-19
por: Sánchez-Rico, Marina, et al.
Publicado: (2023)

Alcohol, tobacco and cannabis use are associated with job loss at follow-up: Findings from the CONSTANCES cohort
por: Airagnes, Guillaume, et al.
Publicado: (2019)

New Molecular Targets for Antidepressant Drugs
por: Kornhuber, Johannes, et al.
Publicado: (2021)

Cardiovascular burden and unemployment: A retrospective study in a large population-based French cohort
por: Sanchez Rico, Marina, et al.
Publicado: (2023)

Distinct cardiovascular and cancer burdens associated with social position, work environment and unemployment: a cross-sectional and retrospective study in a large population-based French cohort
por: Sanchez Rico, Marina, et al.
Publicado: (2023)

Author Correction: A stochastic agent-based model of the SARS-CoV-2 epidemic in France
por: Hoertel, Nicolas, et al.
Publicado: (2020)

Prevalence of Contraindications to Nirmatrelvir-Ritonavir Among Hospitalized Patients With COVID-19 at Risk for Progression to Severe Disease
por: Hoertel, Nicolas, et al.
Publicado: (2022)

Long-term care utilization within older adults with schizophrenia: Associated factors in a multicenter study
por: Pierre, L., et al.
Publicado: (2023)

Repurposing FIASMAs against Acid Sphingomyelinase for COVID-19: A Computational Molecular Docking and Dynamic Simulation Approach
por: Naz, Aliza, et al.
Publicado: (2023)

Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory
por: Zoicas, Iulia, et al.
Publicado: (2016)

Antipsychotic use and 28-day Mortality in Patients Hospitalized with COVID-19: a multicenter observational retrospective study
por: Sánchez-Rico, Marina, et al.
Publicado: (2023)

Association between Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) and Reduced Risk of Death in COVID-19 Patients: A Retrospective Cohort Study
por: Darquennes, Gil, et al.
Publicado: (2021)

Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine
por: Schloer, Sebastian, et al.
Publicado: (2020)

Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls
por: Mühle, Christiane, et al.
Publicado: (2018)

Association of Antihypertensive Agents with the Risk of In-Hospital Death in Patients with Covid-19
por: Chouchana, Laurent, et al.
Publicado: (2021)

Correction to: Association of Antihypertensive Agents with the Risk of In-Hospital Death in Patients with Covid-19
por: Chouchana, Laurent, et al.
Publicado: (2021)

Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma
por: Schumacher, Fabian, et al.
Publicado: (2022)

Authors’ Reply to Mazza et al.: “Fluvoxamine for the Early Treatment of SARS‑CoV‑2 Infection: A Review of Current Evidence”
por: Lenze, Eric J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ov2lieuv9kffgdjvv1fjbh37ui