A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer

Cutaneous metastasis of breast cancer carries a poor prognosis, invokes a poor quality of life, and increases mortality by raising one’s risk of bleeding and infection. Currently, options for treatment are systemic chemotherapy, surgical resection and radiation. These treatments are invasive and can...

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Autores principales: Nguyen, Anthony L, Chong, Esther G, Lee, Joanne, Mirshahidi, Saied, Mirshahidi, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239964/
https://www.ncbi.nlm.nih.gov/pubmed/34249290
http://dx.doi.org/10.1177/2036361320975748
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author Nguyen, Anthony L
Chong, Esther G
Lee, Joanne
Mirshahidi, Saied
Mirshahidi, Hamid
author_facet Nguyen, Anthony L
Chong, Esther G
Lee, Joanne
Mirshahidi, Saied
Mirshahidi, Hamid
author_sort Nguyen, Anthony L
collection PubMed
description Cutaneous metastasis of breast cancer carries a poor prognosis, invokes a poor quality of life, and increases mortality by raising one’s risk of bleeding and infection. Currently, options for treatment are systemic chemotherapy, surgical resection and radiation. These treatments are invasive and can have toxic side effects. A 50-year-old African-American woman with stage IV breast cancer with cutaneous metastasis to the left anterior chest and left supraclavicular area was successfully treated with topical imiquimod. She experienced improvement in appearance and symptoms within several months of starting treatment, resulting in near resolution of her cutaneous metastasis. Imiquimod is currently approved for several cutaneous conditions and has the potential to treat cutaneous metastasis of breast cancer.
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spelling pubmed-82399642021-07-08 A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer Nguyen, Anthony L Chong, Esther G Lee, Joanne Mirshahidi, Saied Mirshahidi, Hamid Rare Tumors Case Report Cutaneous metastasis of breast cancer carries a poor prognosis, invokes a poor quality of life, and increases mortality by raising one’s risk of bleeding and infection. Currently, options for treatment are systemic chemotherapy, surgical resection and radiation. These treatments are invasive and can have toxic side effects. A 50-year-old African-American woman with stage IV breast cancer with cutaneous metastasis to the left anterior chest and left supraclavicular area was successfully treated with topical imiquimod. She experienced improvement in appearance and symptoms within several months of starting treatment, resulting in near resolution of her cutaneous metastasis. Imiquimod is currently approved for several cutaneous conditions and has the potential to treat cutaneous metastasis of breast cancer. SAGE Publications 2021-06-24 /pmc/articles/PMC8239964/ /pubmed/34249290 http://dx.doi.org/10.1177/2036361320975748 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Nguyen, Anthony L
Chong, Esther G
Lee, Joanne
Mirshahidi, Saied
Mirshahidi, Hamid
A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer
title A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer
title_full A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer
title_fullStr A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer
title_full_unstemmed A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer
title_short A case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer
title_sort case report of imiquimod topical therapy as treatment for cutaneous metastasis of breast cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239964/
https://www.ncbi.nlm.nih.gov/pubmed/34249290
http://dx.doi.org/10.1177/2036361320975748
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