Gastric hepatoid carcinoma: Report of a case

Gastric hepatoid carcinoma (GHC) is a rare type of gastric cancer with a tendency to have poor prognosis and metastasize to the liver. GHCs generally show histopathologically hepatocellular differentiation and secrete alpha fetoprotein (AFP). AFP production can occur in cancers originating from the...

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Detalles Bibliográficos
Autores principales: Leblebici, Metin, Erol, Cem Ilgın, Ekinci, Ozgur, Gunduz, Nesrin, Kilic, Furkan, Acar, Mehmet, Eren, Tunc, Girgin, Rabia Burcin, Alimoglu, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240236/
https://www.ncbi.nlm.nih.gov/pubmed/34222816
http://dx.doi.org/10.14744/nci.2020.97720
Descripción
Sumario:Gastric hepatoid carcinoma (GHC) is a rare type of gastric cancer with a tendency to have poor prognosis and metastasize to the liver. GHCs generally show histopathologically hepatocellular differentiation and secrete alpha fetoprotein (AFP). AFP production can occur in cancers originating from the embryologically similar liver, gastrointestinal tract, and yolk sac and often metastasizes to the liver. Although GHC is aggressive, it may not always cause liver metastasis and may invade into the other abdominal organs by direct contact. In this article, we present a case of locally advanced GHC with high AFP levels.

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