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Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice

BACKGROUND: Thymosin β4 (Tβ4) is the most abundant member of the β-thymosins and plays an important role in the control of actin polymerization in eukaryotic cells. While its effects in multiple organs and diseases are being widely investigated, the safety profile has been established in animals and...

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Detalles Bibliográficos
Autores principales:	Wang, Meng, Feng, Li-Rong, Li, Zi-Long, Ma, Kai-Ge, Chang, Ke-Wei, Chen, Xin-Lin, Yang, Peng-Bo, Ji, Sheng-Feng, Ma, Yan-Bing, Han, Hua, Ruganzua, John Bosco, Yang, Wei-Na, Qian, Yi-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240373/ https://www.ncbi.nlm.nih.gov/pubmed/34183019 http://dx.doi.org/10.1186/s12974-021-02166-3

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