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Expression of miR-195 and its target gene Bcl-2 in human intervertebral disc degeneration and their effects on nucleus pulposus cell apoptosis

OBJECTIVE: To investigate the expression of miR-195 and its target gene Bcl-2 in intervertebral disc degeneration (IVDD) and its effect on nucleus pulposus (NP) cell apoptosis. METHODS: The expressions of miR-195 and Bcl-2 in NP tissues of IVDD patients were quantified by qRT-PCR and western blottin...

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Detalles Bibliográficos
Autores principales: Lin, Xue-Lin, Zheng, Zhao-Yun, Zhang, Qing-Shan, Zhang, Zhen, An, You-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240386/
https://www.ncbi.nlm.nih.gov/pubmed/34183039
http://dx.doi.org/10.1186/s13018-021-02538-8