High-resolution crystal structure of the Borreliella burgdorferi PlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain

In the tick-borne pathogens, Borreliella burgdorferi and Borrelia hermsii, c-di-GMP is produced by a single diguanylate cyclase (Rrp1). In these pathogens, the Plz proteins (PlzA, B and C) are the only c-di-GMP receptors identified to date and PlzA is the sole c-di-GMP receptor found in all Borrelie...

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Detalles Bibliográficos
Autores principales: Singh, Avinash, Izac, Jerilyn R, Schuler, Edward J A, Patel, Dhara T, Davies, Christopher, Marconi, Richard T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240479/
https://www.ncbi.nlm.nih.gov/pubmed/34117751
http://dx.doi.org/10.1093/femspd/ftab030

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