Identification of cross-reactive CD8(+) T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants

Despite the growing knowledge of T cell responses in COVID-19 patients, there is a lack of detailed characterizations for T cell-antigen interactions and T cell functions. Here, with a predicted peptide library from SARS-CoV-2 S and N proteins, we found that specific CD8(+) T cell responses were ide...

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Detalles Bibliográficos
Autores principales: Hu, Chao, Shen, Meiying, Han, Xiaojian, Chen, Qian, Li, Luo, Chen, Siyin, Zhang, Jing, Gao, Fengxia, Wang, Wang, Wang, Yingming, Li, Tingting, Li, Shenglong, Huang, Jingjing, Wang, Jianwei, Zhu, Ju, Chen, Dan, Wu, Qingchen, Tao, Kun, Pang, Da, Jin, Aishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240504/
https://www.ncbi.nlm.nih.gov/pubmed/34222571
http://dx.doi.org/10.1016/j.gendis.2021.05.006

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