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Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review
Yolk sac tumors (YSTs) of the endometrium and the broad ligament are very rare, with only 29 cases and one case of each other reported before in the English literature. Due to lack of standard guidelines, the treatment strategies of these diseases are controversial. Here, we share two cases of YSTs...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240588/ https://www.ncbi.nlm.nih.gov/pubmed/34211846 http://dx.doi.org/10.3389/fonc.2021.672434 |
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author | Cheng, Xianzhong Zhao, Qian Xu, Xia Guo, Wenwen Gu, Hongyuan Zhou, Rui Chen, Chen Ma, Dawei Wu, Yinan Ni, Jing Chen, Xiaoxiang |
author_facet | Cheng, Xianzhong Zhao, Qian Xu, Xia Guo, Wenwen Gu, Hongyuan Zhou, Rui Chen, Chen Ma, Dawei Wu, Yinan Ni, Jing Chen, Xiaoxiang |
author_sort | Cheng, Xianzhong |
collection | PubMed |
description | Yolk sac tumors (YSTs) of the endometrium and the broad ligament are very rare, with only 29 cases and one case of each other reported before in the English literature. Due to lack of standard guidelines, the treatment strategies of these diseases are controversial. Here, we share two cases of YSTs originating from the endometrium and the broad ligament respectively and review related literature. A 35-year-old woman was diagnosed with endometrial YST in our center and underwent surgery followed by chemotherapy with BEP (bleomycin, cisplatin and etoposide) regimen for six courses. After follow-up for 21 months, there is still no evidence of relapse. Another 36-year-old woman was admitted to our department with YST of the broad ligament. She was treated with surgery followed by chemotherapy with BEP regimen and was lost to follow-up after completing therapy. The case of endometrial YST we shared was similar to cases reported before, while the case with YST of the broad ligament we shared was the second case reported worldwide. Both of these two cases were treated with surgery combined with chemotherapy with BEP regimen. |
format | Online Article Text |
id | pubmed-8240588 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82405882021-06-30 Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review Cheng, Xianzhong Zhao, Qian Xu, Xia Guo, Wenwen Gu, Hongyuan Zhou, Rui Chen, Chen Ma, Dawei Wu, Yinan Ni, Jing Chen, Xiaoxiang Front Oncol Oncology Yolk sac tumors (YSTs) of the endometrium and the broad ligament are very rare, with only 29 cases and one case of each other reported before in the English literature. Due to lack of standard guidelines, the treatment strategies of these diseases are controversial. Here, we share two cases of YSTs originating from the endometrium and the broad ligament respectively and review related literature. A 35-year-old woman was diagnosed with endometrial YST in our center and underwent surgery followed by chemotherapy with BEP (bleomycin, cisplatin and etoposide) regimen for six courses. After follow-up for 21 months, there is still no evidence of relapse. Another 36-year-old woman was admitted to our department with YST of the broad ligament. She was treated with surgery followed by chemotherapy with BEP regimen and was lost to follow-up after completing therapy. The case of endometrial YST we shared was similar to cases reported before, while the case with YST of the broad ligament we shared was the second case reported worldwide. Both of these two cases were treated with surgery combined with chemotherapy with BEP regimen. Frontiers Media S.A. 2021-06-11 /pmc/articles/PMC8240588/ /pubmed/34211846 http://dx.doi.org/10.3389/fonc.2021.672434 Text en Copyright © 2021 Cheng, Zhao, Xu, Guo, Gu, Zhou, Chen, Ma, Wu, Ni and Chen https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Cheng, Xianzhong Zhao, Qian Xu, Xia Guo, Wenwen Gu, Hongyuan Zhou, Rui Chen, Chen Ma, Dawei Wu, Yinan Ni, Jing Chen, Xiaoxiang Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review |
title | Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review |
title_full | Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review |
title_fullStr | Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review |
title_full_unstemmed | Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review |
title_short | Case Report: Extragonadal Yolk Sac Tumors Originating From the Endometrium and the Broad Ligament: A Case Series and Literature Review |
title_sort | case report: extragonadal yolk sac tumors originating from the endometrium and the broad ligament: a case series and literature review |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240588/ https://www.ncbi.nlm.nih.gov/pubmed/34211846 http://dx.doi.org/10.3389/fonc.2021.672434 |
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