Cargando…

High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility

Multiple sclerosis (MS) susceptibility shows strong genetic associations with HLA alleles and haplotypes. We genotyped 11 HLA genes in 477 non-Hispanic European MS patients and their 954 unaffected parents using a validated next-generation sequencing (NGS) methodology. HLA haplotypes were assigned u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Osoegawa, Kazutoyo, Creary, Lisa E., Montero-Martín, Gonzalo, Mallempati, Kalyan C., Gangavarapu, Sridevi, Caillier, Stacy J., Santaniello, Adam, Isobe, Noriko, Hollenbach, Jill A., Hauser, Stephen L., Oksenberg, Jorge R., Fernández-Viňa, Marcelo A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240666/ https://www.ncbi.nlm.nih.gov/pubmed/34211458 http://dx.doi.org/10.3389/fimmu.2021.644838

Ejemplares similares

Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations
por: Creary, Lisa E., et al.
Publicado: (2021)

A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson’s disease
por: Hollenbach, Jill A., et al.
Publicado: (2019)

The killer immunoglobulin-like receptor KIR3DL1 combination with HLA-Bw4 is protective against multiple sclerosis in African Americans
por: Hollenbach, Jill A., et al.
Publicado: (2016)

High Resolution HLA Analysis Reveals Independent Class I Haplotypes and Amino-Acid Motifs Protective for Multiple Sclerosis
por: Mack, Steven J., et al.
Publicado: (2018)

Generation and expression analysis of BAC humanized mice carrying HLA‐DP401 haplotype
por: Li, Feng, et al.
Publicado: (2021)

HLA class II regulation and structure. Analysis with HLA-DR3 and HLA-DP point mutants
Publicado: (1985)

Standard reference sequences for submission of HLA genotyping for the 18th International HLA and Immunogenetics Workshop
por: Matern, Benedict M., et al.
Publicado: (2021)

Structural requirements for pairing of alpha and beta chains in HLA-DR and HLA-DP molecules
Publicado: (1990)

A combined DPA1∼DPB1 amino acid epitope is the primary unit of selection on the HLA-DP heterodimer
por: Hollenbach, Jill A., et al.
Publicado: (2012)

Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans
por: Barquera, Rodrigo, et al.
Publicado: (2020)

Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression
por: Barbour, Jason D, et al.
Publicado: (2007)

KIR and HLA haplotype analysis in a family lacking the KIR 2DL1-2DP1 genes
por: Vojvodić, S, et al.
Publicado: (2015)

Correction: Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression
por: Barbour, Jason D, et al.
Publicado: (2007)

Peptide binding predictions for HLA DR, DP and DQ molecules
por: Wang, Peng, et al.
Publicado: (2010)

T cells sensitized to synthetic HLA-DR3 peptide give evidence of continuous presentation of denatured HLA-DR3 molecules by HLA-DP
Publicado: (1989)

Assessment of HLA-DPB1 genetic variation using an HLA-DP tool and its implications in clinical transplantation
por: Sajulga, Ray, et al.
Publicado: (2023)

HLA allele and haplotype frequencies of registered stem cell donors in Chile
por: Solloch, Ute V., et al.
Publicado: (2023)

Human T cells recognize HLA-DP–bound peptides in two orientations
por: Klobuch, Sebastian, et al.
Publicado: (2022)

HLA Diversity in Saudi Population: High Frequency of Homozygous HLA Alleles and Haplotypes
por: Chentoufi, Aziz Alami, et al.
Publicado: (2022)

Development of a Humanized HLA-A2.1/DP4 Transgenic Mouse Model and the Use of This Model to Map HLA-DP4-Restricted Epitopes of HBV Envelope Protein
por: Ru, Zhitao, et al.
Publicado: (2012)

HLA-G UTR Haplotype Conservation in the Malian Population: Association with Soluble HLA-G
por: Carlini, Federico, et al.
Publicado: (2013)

HLA Haplotype Mismatch Transplants and Posttransplant Cyclophosphamide
por: Bacigalupo, Andrea, et al.
Publicado: (2016)

HLA Polymorphisms and Haplotype Diversity in Transylvania, Romania
por: Vică, Mihaela L., et al.
Publicado: (2019)

HLA haplotype frequencies and diversity in patients with hemoglobinopathies
por: Scigliuolo, Graziana M., et al.
Publicado: (2023)

Haplotypes of the HLA-G 3’ Untranslated Region Respond to Endogenous Factors of HLA-G+ and HLA-G- Cell Lines Differentially
por: Poras, Isabelle, et al.
Publicado: (2017)

HLA Diversity in the 1000 Genomes Dataset
por: Gourraud, Pierre-Antoine, et al.
Publicado: (2014)

Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset
por: Khankhanian, Pouya, et al.
Publicado: (2010)

Complementarity of Binding Motifs is a General Property of HLA-A and HLA-B Molecules and Does Not Seem to Effect HLA Haplotype Composition
por: Rao, Xiangyu, et al.
Publicado: (2013)

Relevance of HLA-DP/DQ and ICAM-1 SNPs among Ovarian Cancer Patients
por: Ghazy, Amany A., et al.
Publicado: (2016)

Correlation of HLA-DP/DQ polymorphisms with transplant etiologies and prognosis in liver transplant recipients
por: Li, Yi, et al.
Publicado: (2017)

Relevance of HLA-DP/DQ and INF-λ4 Polymorphisms to COVID-19 Outcomes
por: Ghazy, Amany A., et al.
Publicado: (2023)

HLA class I haplotype diversity is consistent with selection for frequent existing haplotypes
por: Alter, Idan, et al.
Publicado: (2017)

HLA haplotypes associated with hemochromatosis mutations in the Spanish population
por: Pacho, Arantza, et al.
Publicado: (2004)

Distribution of HLA class I alleles and haplotypes in Korean.
por: Kim, T. G., et al.
Publicado: (1993)

Mapping the genetic diversity of HLA haplotypes in the Japanese populations
por: Saw, Woei-Yuh, et al.
Publicado: (2015)

HLA-G Haplotypes Are Differentially Associated with Asthmatic Features
por: Ribeyre, Camille, et al.
Publicado: (2018)

HLA-class II haplotypes and Autism Spectrum Disorders
por: Bennabi, Meriem, et al.
Publicado: (2018)

Should results of HLA haplotype frequency estimations be normalized?
por: Seitz, Susanne, et al.
Publicado: (2021)

HLA alleles and haplotypes in Sudanese population and their relationship with Mediterraneans
por: Suarez-Trujillo, Fabio, et al.
Publicado: (2023)

Soluble HLA‐G levels in seminal plasma are associated with HLA‐G 3′UTR genotypes and haplotypes
por: Craenmehr, Moniek H. C., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qm6dnqbgte6khin795po4887uq