Cargando…

Prevalence and Causes of Hyperuricemia in Children

Introduction  There are various factors responsible for hyperuricemia in children, however, there is extremely limited local data available. In this study, we aim to determine the causes and risk factors associated with hyperuricemia. This study will assist pediatric consultants to identify children...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Jatender, Gupta, Aarzoo, Dev, Kapeel, Kumar, Sameet, Kataria, Deepak, Gul, Ambresha, Abbas, Mohammed, Jamil, Amna, Shahid, Simra, Memon, Sidra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240676/
https://www.ncbi.nlm.nih.gov/pubmed/34235007
http://dx.doi.org/10.7759/cureus.15307
_version_ 1783715255277322240
author Kumar, Jatender
Gupta, Aarzoo
Dev, Kapeel
Kumar, Sameet
Kataria, Deepak
Gul, Ambresha
Abbas, Mohammed
Jamil, Amna
Shahid, Simra
Memon, Sidra
author_facet Kumar, Jatender
Gupta, Aarzoo
Dev, Kapeel
Kumar, Sameet
Kataria, Deepak
Gul, Ambresha
Abbas, Mohammed
Jamil, Amna
Shahid, Simra
Memon, Sidra
author_sort Kumar, Jatender
collection PubMed
description Introduction  There are various factors responsible for hyperuricemia in children, however, there is extremely limited local data available. In this study, we aim to determine the causes and risk factors associated with hyperuricemia. This study will assist pediatric consultants to identify children who might be at risk of hyperuricemia and manage them accordingly. Methods This study was conducted in pediatric outpatient departments of various tertiary care hospitals from January 2018 to December 2019. Five thousand (n = 5000) children of either gender between the age group of 1-14 years, were enrolled in the study after informed consent from their parents. Uric acid levels were assessed by using the UASure blood uric acid monitoring handheld device. Results  In our study, n = 1301 (26.02%) children had hyperuricemia. Hyperuricemia was more common in male compared to females (65.49% vs. 34.51%; p-value <0.00001) and in older children (9 ± 2 years vs. 7 ± 3; p-value <0.00001). In hyperuricemia patients, the most common disorder was gastroenteritis (23.98%), followed by respiratory infection (23.14%) and asthma (15.45%). Conclusion  Hyperuricemia in children is very prevalent in the local setting. Patients with pre-existing conditions like congenital heart disease, asthma, epilepsy, and cancers should routinely be screened for hyperuricemia and managed accordingly to avoid long-term complications associated with hyperuricemia.
format Online
Article
Text
id pubmed-8240676
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-82406762021-07-06 Prevalence and Causes of Hyperuricemia in Children Kumar, Jatender Gupta, Aarzoo Dev, Kapeel Kumar, Sameet Kataria, Deepak Gul, Ambresha Abbas, Mohammed Jamil, Amna Shahid, Simra Memon, Sidra Cureus Internal Medicine Introduction  There are various factors responsible for hyperuricemia in children, however, there is extremely limited local data available. In this study, we aim to determine the causes and risk factors associated with hyperuricemia. This study will assist pediatric consultants to identify children who might be at risk of hyperuricemia and manage them accordingly. Methods This study was conducted in pediatric outpatient departments of various tertiary care hospitals from January 2018 to December 2019. Five thousand (n = 5000) children of either gender between the age group of 1-14 years, were enrolled in the study after informed consent from their parents. Uric acid levels were assessed by using the UASure blood uric acid monitoring handheld device. Results  In our study, n = 1301 (26.02%) children had hyperuricemia. Hyperuricemia was more common in male compared to females (65.49% vs. 34.51%; p-value <0.00001) and in older children (9 ± 2 years vs. 7 ± 3; p-value <0.00001). In hyperuricemia patients, the most common disorder was gastroenteritis (23.98%), followed by respiratory infection (23.14%) and asthma (15.45%). Conclusion  Hyperuricemia in children is very prevalent in the local setting. Patients with pre-existing conditions like congenital heart disease, asthma, epilepsy, and cancers should routinely be screened for hyperuricemia and managed accordingly to avoid long-term complications associated with hyperuricemia. Cureus 2021-05-28 /pmc/articles/PMC8240676/ /pubmed/34235007 http://dx.doi.org/10.7759/cureus.15307 Text en Copyright © 2021, Kumar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kumar, Jatender
Gupta, Aarzoo
Dev, Kapeel
Kumar, Sameet
Kataria, Deepak
Gul, Ambresha
Abbas, Mohammed
Jamil, Amna
Shahid, Simra
Memon, Sidra
Prevalence and Causes of Hyperuricemia in Children
title Prevalence and Causes of Hyperuricemia in Children
title_full Prevalence and Causes of Hyperuricemia in Children
title_fullStr Prevalence and Causes of Hyperuricemia in Children
title_full_unstemmed Prevalence and Causes of Hyperuricemia in Children
title_short Prevalence and Causes of Hyperuricemia in Children
title_sort prevalence and causes of hyperuricemia in children
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240676/
https://www.ncbi.nlm.nih.gov/pubmed/34235007
http://dx.doi.org/10.7759/cureus.15307
work_keys_str_mv AT kumarjatender prevalenceandcausesofhyperuricemiainchildren
AT guptaaarzoo prevalenceandcausesofhyperuricemiainchildren
AT devkapeel prevalenceandcausesofhyperuricemiainchildren
AT kumarsameet prevalenceandcausesofhyperuricemiainchildren
AT katariadeepak prevalenceandcausesofhyperuricemiainchildren
AT gulambresha prevalenceandcausesofhyperuricemiainchildren
AT abbasmohammed prevalenceandcausesofhyperuricemiainchildren
AT jamilamna prevalenceandcausesofhyperuricemiainchildren
AT shahidsimra prevalenceandcausesofhyperuricemiainchildren
AT memonsidra prevalenceandcausesofhyperuricemiainchildren