Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature

Plasmablastic lymphoma (PBL) is an aggressive lymphoma commonly associated with HIV infection. It most commonly presents in the oral cavity and rarely involves the kidney. Herein, we report a case of HIV positive male with renal involvement of PBL. The patient presented with unilateral severe hydron...

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Autores principales: Sapkota, Sulav, Priyadarshini, Mona, Hazarika, Diganta, Swamy, Shivakumar, Naik, Radheshyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240923/
https://www.ncbi.nlm.nih.gov/pubmed/34267442
http://dx.doi.org/10.4103/ijn.IJN_277_18
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author Sapkota, Sulav
Priyadarshini, Mona
Hazarika, Diganta
Swamy, Shivakumar
Naik, Radheshyam
author_facet Sapkota, Sulav
Priyadarshini, Mona
Hazarika, Diganta
Swamy, Shivakumar
Naik, Radheshyam
author_sort Sapkota, Sulav
collection PubMed
description Plasmablastic lymphoma (PBL) is an aggressive lymphoma commonly associated with HIV infection. It most commonly presents in the oral cavity and rarely involves the kidney. Herein, we report a case of HIV positive male with renal involvement of PBL. The patient presented with unilateral severe hydronephrosis with unaltered renal functions. Despite aggressive management, there was an early relapse and the patient died within 2 years of the diagnosis. Despite the recent advances in the therapy of HIV-associated aggressive lymphomas, patients with PBL have a poor prognosis. Multimodal treatment with chemotherapy, newer targeted and biological agents, along with hematopoietic stem cell transplantation is essential for the treatment of PBL.
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spelling pubmed-82409232021-07-14 Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature Sapkota, Sulav Priyadarshini, Mona Hazarika, Diganta Swamy, Shivakumar Naik, Radheshyam Indian J Nephrol Case Report Plasmablastic lymphoma (PBL) is an aggressive lymphoma commonly associated with HIV infection. It most commonly presents in the oral cavity and rarely involves the kidney. Herein, we report a case of HIV positive male with renal involvement of PBL. The patient presented with unilateral severe hydronephrosis with unaltered renal functions. Despite aggressive management, there was an early relapse and the patient died within 2 years of the diagnosis. Despite the recent advances in the therapy of HIV-associated aggressive lymphomas, patients with PBL have a poor prognosis. Multimodal treatment with chemotherapy, newer targeted and biological agents, along with hematopoietic stem cell transplantation is essential for the treatment of PBL. Wolters Kluwer - Medknow 2021 2021-02-08 /pmc/articles/PMC8240923/ /pubmed/34267442 http://dx.doi.org/10.4103/ijn.IJN_277_18 Text en Copyright: © 2021 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sapkota, Sulav
Priyadarshini, Mona
Hazarika, Diganta
Swamy, Shivakumar
Naik, Radheshyam
Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature
title Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature
title_full Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature
title_fullStr Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature
title_full_unstemmed Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature
title_short Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature
title_sort plasmablastic lymphoma involving kidney in an hiv positive patient: a case report with review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240923/
https://www.ncbi.nlm.nih.gov/pubmed/34267442
http://dx.doi.org/10.4103/ijn.IJN_277_18
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