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Electrosteric stealth Rivastigmine loaded liposomes for brain targeting: preparation, characterization, ex vivo, bio-distribution and in vivo pharmacokinetic studies
Being one of the highly effective drugs in treatment of Alzheimer’s disease, Rivastigmine brain targeting is highly demandable, therefore liposomal dispersion of Rivastigmine was prepared containing 2 mol% PEG-DSPE added to Lecithin, Didecyldimethyl ammonium bromide (DDAB), Tween 80 in 1:0.02:0.25 m...
Autores principales: | Nageeb El-Helaly, Sara, Abd Elbary, Ahmed, Kassem, Mohamed A., El-Nabarawi, Mohamed A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240971/ https://www.ncbi.nlm.nih.gov/pubmed/28415883 http://dx.doi.org/10.1080/10717544.2017.1309476 |
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