Cargando…

Mathematical modeling of intraperitoneal drug delivery: simulation of drug distribution in a single tumor nodule

The intraperitoneal (IP) administration of chemotherapy is an alternative treatment for peritoneal carcinomatosis, allowing for higher intratumor concentrations of the cytotoxic agent compared to intravenous administration. Nevertheless, drug penetration depths are still limited to a few millimeters...

Descripción completa

Detalles Bibliográficos
Autores principales:	Steuperaert, Margo, Falvo D’Urso Labate, Giuseppe, Debbaut, Charlotte, De Wever, Olivier, Vanhove, Christian, Ceelen, Wim, Segers, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240979/ https://www.ncbi.nlm.nih.gov/pubmed/28181817 http://dx.doi.org/10.1080/10717544.2016.1269848

Ejemplares similares

A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy
por: Steuperaert, Margo, et al.
Publicado: (2019)

Optimization of intraperitoneal aerosolized drug delivery using computational fluid dynamics (CFD) modeling
por: Rahimi-Gorji, Mohammad, et al.
Publicado: (2022)

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model
por: Gremonprez, Félix, et al.
Publicado: (2015)

Albumin-based cancer therapeutics for intraperitoneal drug delivery: a review
por: Van de Sande, Leen, et al.
Publicado: (2019)

Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers
por: De Vlieghere, Elly, et al.
Publicado: (2016)

Optimization of Drug Delivery Systems for Intraperitoneal Therapy to Extend the Residence Time of the Chemotherapeutic Agent
por: De Smet, L., et al.
Publicado: (2013)

Image-Based Modeling of Drug Delivery during Intraperitoneal Chemotherapy in a Heterogeneous Tumor Nodule
por: Rezaeian, Mohsen, et al.
Publicado: (2023)

Mathematical Modeling of Targeted Drug Delivery Using Magnetic Nanoparticles during Intraperitoneal Chemotherapy
por: Rezaeian, Mohsen, et al.
Publicado: (2022)

Hyperthermic Intraperitoneal Chemotherapy: A Critical Review
por: Ceelen, Wim, et al.
Publicado: (2021)

Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection
por: Melsens, Elodie, et al.
Publicado: (2017)

Magnetically assisted intraperitoneal drug delivery for cancer chemotherapy
por: Shamsi, Milad, et al.
Publicado: (2018)

Assessment of Ovarian Cancer Tumors Treated with Intraperitoneal Cisplatin Therapy by Nanoscopic X-ray Fluorescence Imaging
por: Laforce, Brecht, et al.
Publicado: (2016)

Effects of Hyperthermia and Hyperthermic Intraperitoneal Chemoperfusion on the Peritoneal and Tumor Immune Contexture
por: Chia, Daryl K. A., et al.
Publicado: (2023)

Rigorous mathematical optimization of synthetic hepatic vascular trees
por: Jessen, Etienne, et al.
Publicado: (2022)

Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
por: Fleten, Karianne Giller, et al.
Publicado: (2022)

BEV-IP: Perioperative chemotherapy with bevacizumab in patients undergoing cytoreduction and intraperitoneal chemoperfusion for colorectal carcinomatosis
por: Willaert, Wouter, et al.
Publicado: (2015)

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment
por: De Vlieghere, Elly, et al.
Publicado: (2023)

Simulating drug penetration during hyperthermic intraperitoneal chemotherapy
por: Löke, Daan R., et al.
Publicado: (2021)

The Feasibility of Pressurised Intraperitoneal Aerosolised Virotherapy (PIPAV) to Administer Oncolytic Adenoviruses
por: Tate, Sophia J., et al.
Publicado: (2021)

Development of rotational intraperitoneal pressurized aerosol chemotherapy to enhance drug delivery into the peritoneum
por: Park, Soo Jin, et al.
Publicado: (2021)

History of intraperitoneal platinum drug delivery for ovarian cancer and its future applications
por: Muggia, Franco, et al.
Publicado: (2021)

Hypoxia imaging with (18)F-FAZA PET/CT predicts radiotherapy response in esophageal adenocarcinoma xenografts
por: Melsens, Elodie, et al.
Publicado: (2018)

Mathematical Modelling, Simulation and Optimisation of Microneedles for Transdermal Drug Delivery: Trends and Progress
por: Yadav, Prateek Ranjan, et al.
Publicado: (2020)

Dentistry and Drug Adverse Events: Between Responsibilities and Regulations
por: D’Anna, Tommaso, et al.
Publicado: (2022)

Establishment of a rat ovarian peritoneal metastasis model to study pressurized intraperitoneal aerosol chemotherapy (PIPAC)
por: Van de Sande, Leen, et al.
Publicado: (2019)

Tumor Penetrating Theranostic Nanoparticles for Enhancement of Targeted and Image-guided Drug Delivery into Peritoneal Tumors following Intraperitoneal Delivery
por: Gao, Ning, et al.
Publicado: (2017)

A Versatile Bioreactor for Dynamic Suspension Cell Culture. Application to the Culture of Cancer Cell Spheroids
por: Massai, Diana, et al.
Publicado: (2016)

Electromotive Enhanced Drug Administration in Oncology: Principles, Evidence, Current and Emerging Applications
por: Min, Jolene Wong Si, et al.
Publicado: (2022)

Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer
por: De Clercq, Kaat, et al.
Publicado: (2019)

Intraperitoneal aerosolization of albumin-stabilized paclitaxel nanoparticles (Abraxane™) for peritoneal carcinomatosis – a phase I first-in-human study
por: Van De Sande, Leen, et al.
Publicado: (2018)

Mathematical Modeling of Release Kinetics from Supramolecular Drug Delivery Systems
por: Mircioiu, Constantin, et al.
Publicado: (2019)

Drug Distribution and Penetration of Foam-Based Intraperitoneal Chemotherapy (FBIC)
por: Khosrawipour, Carolina, et al.
Publicado: (2023)

Effect of Particle Carriers for Intraperitoneal Drug Delivery on the Course of Ovarian Cancer and Its Immune Microenvironment in a Mouse Model
por: Wouters, Roxanne, et al.
Publicado: (2022)

Mimics of Duplication Cysts: Intraperitoneal Nodules in a 14-Year-Old Boy
por: Ohanessian, Sara E, et al.
Publicado: (2015)

Phase I study of intraperitoneal aerosolized nanoparticle albumin based paclitaxel (NAB-PTX) for unresectable peritoneal metastases
por: Ceelen, Wim, et al.
Publicado: (2022)

Drug delivery and nanoparticles: Applications and hazards
por: De Jong, Wim H, et al.
Publicado: (2008)

Drug Sensitivity Testing in Cytoreductive Surgery and Intraperitoneal Chemotherapy of Pseudomyxoma Peritonei
por: Bjersand, Kathrine, et al.
Publicado: (2015)

A real-time ex vivo model (eIBUB) for optimizing intraperitoneal drug delivery as an alternative to living animal models
por: Sautkin, Iaroslav, et al.
Publicado: (2019)

Discrete-event simulation study of a COVID-19 mass vaccination centre
por: Sala, Francesca, et al.
Publicado: (2023)

Thermosensitive Liposome-Mediated Drug Delivery in Chemotherapy: Mathematical Modelling for Spatio–temporal Drug Distribution and Model-Based Optimisation
por: Huang, Yu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lfgi5v6hq8qgl8ic1gsltrgv5s