Cargando…

“SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa

Reducing diagnostic delay is key toward decreasing tuberculosis-associated deaths in people living with human immunodeficiency virus. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89%...

Descripción completa

Detalles Bibliográficos
Autores principales: Sossen, Bianca, Broger, Tobias, Kerkhoff, Andrew D, Schutz, Charlotte, Trollip, Andre, Moreau, Emmanuel, Schumacher, Samuel G, Burton, Rosie, Ward, Amy, Wilkinson, Robert J, Barr, David A, Nicol, Mark P, Denkinger, Claudia M, Meintjes, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240995/
https://www.ncbi.nlm.nih.gov/pubmed/31917832
http://dx.doi.org/10.1093/cid/ciaa024
_version_ 1783715315187712000
author Sossen, Bianca
Broger, Tobias
Kerkhoff, Andrew D
Schutz, Charlotte
Trollip, Andre
Moreau, Emmanuel
Schumacher, Samuel G
Burton, Rosie
Ward, Amy
Wilkinson, Robert J
Barr, David A
Nicol, Mark P
Denkinger, Claudia M
Meintjes, Graeme
author_facet Sossen, Bianca
Broger, Tobias
Kerkhoff, Andrew D
Schutz, Charlotte
Trollip, Andre
Moreau, Emmanuel
Schumacher, Samuel G
Burton, Rosie
Ward, Amy
Wilkinson, Robert J
Barr, David A
Nicol, Mark P
Denkinger, Claudia M
Meintjes, Graeme
author_sort Sossen, Bianca
collection PubMed
description Reducing diagnostic delay is key toward decreasing tuberculosis-associated deaths in people living with human immunodeficiency virus. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86–97%.
format Online
Article
Text
id pubmed-8240995
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-82409952021-06-30 “SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa Sossen, Bianca Broger, Tobias Kerkhoff, Andrew D Schutz, Charlotte Trollip, Andre Moreau, Emmanuel Schumacher, Samuel G Burton, Rosie Ward, Amy Wilkinson, Robert J Barr, David A Nicol, Mark P Denkinger, Claudia M Meintjes, Graeme Clin Infect Dis Brief Reports and Commentaries Reducing diagnostic delay is key toward decreasing tuberculosis-associated deaths in people living with human immunodeficiency virus. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86–97%. Oxford University Press 2020-01-09 /pmc/articles/PMC8240995/ /pubmed/31917832 http://dx.doi.org/10.1093/cid/ciaa024 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports and Commentaries
Sossen, Bianca
Broger, Tobias
Kerkhoff, Andrew D
Schutz, Charlotte
Trollip, Andre
Moreau, Emmanuel
Schumacher, Samuel G
Burton, Rosie
Ward, Amy
Wilkinson, Robert J
Barr, David A
Nicol, Mark P
Denkinger, Claudia M
Meintjes, Graeme
“SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa
title “SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa
title_full “SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa
title_fullStr “SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa
title_full_unstemmed “SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa
title_short “SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa
title_sort “silvamp tb lam” rapid urine tuberculosis test predicts mortality in patients hospitalized with human immunodeficiency virus in south africa
topic Brief Reports and Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240995/
https://www.ncbi.nlm.nih.gov/pubmed/31917832
http://dx.doi.org/10.1093/cid/ciaa024
work_keys_str_mv AT sossenbianca silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT brogertobias silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT kerkhoffandrewd silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT schutzcharlotte silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT trollipandre silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT moreauemmanuel silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT schumachersamuelg silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT burtonrosie silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT wardamy silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT wilkinsonrobertj silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT barrdavida silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT nicolmarkp silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT denkingerclaudiam silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica
AT meintjesgraeme silvamptblamrapidurinetuberculosistestpredictsmortalityinpatientshospitalizedwithhumanimmunodeficiencyvirusinsouthafrica