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A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo
The epidermal growth factor receptor (EGFR) is an important anti-tumor target. The development of novel molecular-targeted anti-tumor drugs that can target the interior of tumor cells and specifically silence EGFR expression is valuable and promising. In this work, a promising anti-tumor conjugate c...
Autores principales: | He, Shuai, Cen, Bohong, Liao, Lumin, Wang, Zhen, Qin, Yixin, Wu, Zhuomin, Liao, Wenjie, Zhang, Zhongyi, Ji, Aimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241002/ https://www.ncbi.nlm.nih.gov/pubmed/28181832 http://dx.doi.org/10.1080/10717544.2016.1267821 |
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