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Marked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice

Our previous works demonstrated that brown rice-specific bioactive substance, γ-oryzanol acts as a chaperone, attenuates exaggerated endoplasmic reticulum (ER) stress in brain hypothalamus and pancreatic islets, thereby ameliorating metabolic derangement in high fat diet (HFD)-induced obese diabetic...

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Detalles Bibliográficos
Autores principales: Kozuka, Chisayo, Shimizu-Okabe, Chigusa, Takayama, Chitoshi, Nakano, Kaku, Morinaga, Hidetaka, Kinjo, Ayano, Fukuda, Kotaro, Kamei, Asuka, Yasuoka, Akihito, Kondo, Takashi, Abe, Keiko, Egashira, Kensuke, Masuzaki, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241037/
https://www.ncbi.nlm.nih.gov/pubmed/28181829
http://dx.doi.org/10.1080/10717544.2017.1279237

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