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Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles

The aim of this study was to establish a paclitaxel (PTX)-loaded mixed micelle delivery system (PTX-TP-M) with vitamin E-TPGS (TPGS) and Plasdone®S-630 Copovidone (PVPS630) as carriers to improve the solubility, oral absorption, and anti-tumor activity of PTX against lung cancer. In this study, PTX-...

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Detalles Bibliográficos
Autores principales: Hou, Jian, Sun, E., Zhang, Zhen-Hai, Wang, Jing, Yang, Lei, Cui, Li, Ke, Zhong-Cheng, Tan, Xiao-Bin, Jia, Xiao-Bin, Lv, Huixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241097/
https://www.ncbi.nlm.nih.gov/pubmed/28165804
http://dx.doi.org/10.1080/10717544.2016.1245370

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