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Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles
The aim of this study was to establish a paclitaxel (PTX)-loaded mixed micelle delivery system (PTX-TP-M) with vitamin E-TPGS (TPGS) and Plasdone®S-630 Copovidone (PVPS630) as carriers to improve the solubility, oral absorption, and anti-tumor activity of PTX against lung cancer. In this study, PTX-...
Autores principales: | Hou, Jian, Sun, E., Zhang, Zhen-Hai, Wang, Jing, Yang, Lei, Cui, Li, Ke, Zhong-Cheng, Tan, Xiao-Bin, Jia, Xiao-Bin, Lv, Huixia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241097/ https://www.ncbi.nlm.nih.gov/pubmed/28165804 http://dx.doi.org/10.1080/10717544.2016.1245370 |
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