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Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making

More than 1.6 million Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) tests were administered daily in the United States at the peak of the epidemic, with a significant focus on individual treatment. Here, we show that objective-driven, strategic sampling designs and analyses can maximi...

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Autores principales: Nichols, James D., Bogich, Tiffany L., Howerton, Emily, Bjørnstad, Ottar N., Borchering, Rebecca K., Ferrari, Matthew, Haran, Murali, Jewell, Christopher, Pepin, Kim M., Probert, William J. M., Pulliam, Juliet R. C., Runge, Michael C., Tildesley, Michael, Viboud, Cécile, Shea, Katriona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241114/
https://www.ncbi.nlm.nih.gov/pubmed/34138840
http://dx.doi.org/10.1371/journal.pbio.3001307
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author Nichols, James D.
Bogich, Tiffany L.
Howerton, Emily
Bjørnstad, Ottar N.
Borchering, Rebecca K.
Ferrari, Matthew
Haran, Murali
Jewell, Christopher
Pepin, Kim M.
Probert, William J. M.
Pulliam, Juliet R. C.
Runge, Michael C.
Tildesley, Michael
Viboud, Cécile
Shea, Katriona
author_facet Nichols, James D.
Bogich, Tiffany L.
Howerton, Emily
Bjørnstad, Ottar N.
Borchering, Rebecca K.
Ferrari, Matthew
Haran, Murali
Jewell, Christopher
Pepin, Kim M.
Probert, William J. M.
Pulliam, Juliet R. C.
Runge, Michael C.
Tildesley, Michael
Viboud, Cécile
Shea, Katriona
author_sort Nichols, James D.
collection PubMed
description More than 1.6 million Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) tests were administered daily in the United States at the peak of the epidemic, with a significant focus on individual treatment. Here, we show that objective-driven, strategic sampling designs and analyses can maximize information gain at the population level, which is necessary to increase situational awareness and predict, prepare for, and respond to a pandemic, while also continuing to inform individual treatment. By focusing on specific objectives such as individual treatment or disease prediction and control (e.g., via the collection of population-level statistics to inform lockdown measures or vaccine rollout) and drawing from the literature on capture–recapture methods to deal with nonrandom sampling and testing errors, we illustrate how public health objectives can be achieved even with limited test availability when testing programs are designed a priori to meet those objectives.
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spelling pubmed-82411142021-07-12 Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making Nichols, James D. Bogich, Tiffany L. Howerton, Emily Bjørnstad, Ottar N. Borchering, Rebecca K. Ferrari, Matthew Haran, Murali Jewell, Christopher Pepin, Kim M. Probert, William J. M. Pulliam, Juliet R. C. Runge, Michael C. Tildesley, Michael Viboud, Cécile Shea, Katriona PLoS Biol Essay More than 1.6 million Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) tests were administered daily in the United States at the peak of the epidemic, with a significant focus on individual treatment. Here, we show that objective-driven, strategic sampling designs and analyses can maximize information gain at the population level, which is necessary to increase situational awareness and predict, prepare for, and respond to a pandemic, while also continuing to inform individual treatment. By focusing on specific objectives such as individual treatment or disease prediction and control (e.g., via the collection of population-level statistics to inform lockdown measures or vaccine rollout) and drawing from the literature on capture–recapture methods to deal with nonrandom sampling and testing errors, we illustrate how public health objectives can be achieved even with limited test availability when testing programs are designed a priori to meet those objectives. Public Library of Science 2021-06-17 /pmc/articles/PMC8241114/ /pubmed/34138840 http://dx.doi.org/10.1371/journal.pbio.3001307 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Essay
Nichols, James D.
Bogich, Tiffany L.
Howerton, Emily
Bjørnstad, Ottar N.
Borchering, Rebecca K.
Ferrari, Matthew
Haran, Murali
Jewell, Christopher
Pepin, Kim M.
Probert, William J. M.
Pulliam, Juliet R. C.
Runge, Michael C.
Tildesley, Michael
Viboud, Cécile
Shea, Katriona
Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making
title Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making
title_full Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making
title_fullStr Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making
title_full_unstemmed Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making
title_short Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making
title_sort strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making
topic Essay
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241114/
https://www.ncbi.nlm.nih.gov/pubmed/34138840
http://dx.doi.org/10.1371/journal.pbio.3001307
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