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A novel biosensor based on intestinal 3D organoids for detecting the function of BCRP

Breast cancer resistance protein (BCRP), a key drug efflux transporter, significantly affects the therapeutic efficacy of many drugs. Thus, screening specific BCRP inhibitors and distinguishing between substrates and non-substrates of BCRP are valuable in drug discovery and development. This study p...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Zhao, Junfang, Liang, Chenmeizi, Liu, Mingyao, Xu, Feng, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241135/
https://www.ncbi.nlm.nih.gov/pubmed/28949254
http://dx.doi.org/10.1080/10717544.2017.1381199